Evidence map›Paper›PMID 32817342›Full record

ArticleThe Journal of biological chemistry2020

A non-canonical role for the DNA glycosylase NEIL3 in suppressing APE1 endonuclease-mediated ssDNA damage.

Anh Ha, Yunfeng Lin, Shan Yan

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Research progress on the role of the NEIL family in cancer.Frontiers in cell and developmental biology · 2025
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Deficiency of NEIL3 Enhances the Chemotherapy Resistance of Prostate Cancer.International journal of molecular sciences · 2021
    Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Anh HaDepartment of Biological Sciences, University of North Carolina at Charlotte, Charlotte, North Carolina, USA.ORCID 0000-0003-2053-1709
Yunfeng LinDepartment of Biological Sciences, University of North Carolina at Charlotte, Charlotte, North Carolina, USA.
Shan YanDepartment of Biological Sciences, University of North Carolina at Charlotte, Charlotte, North Carolina, USA shan.yan@uncc.edu.ORCID 0000-0001-8106-6295
University of North Carolina at Charlotte · US

Funding

Mechanism of APE1 in DNA damage responseR01CA225637 · NCI · UNIVERSITY OF NORTH CAROLINA CHARLOTTE · PI YAN, SHAN · 2018 to 2022
$1.9M
Role of APE2 in DNA damage responseR15GM114713 · NIGMS · UNIVERSITY OF NORTH CAROLINA CHARLOTTE · PI YAN, SHAN · 2015 to 2015
$363k
Acquisition of a Microscale Thermophoresis InstrumentS10OD026970 · OD · UNIVERSITY OF NORTH CAROLINA CHARLOTTE · PI NESMELOVA, IRINA V · 2019 to 2019
$143k
NCI NIH HHS R01 CA225637NIGMS NIH HHS R15 GM114713NIH HHS S10 OD026970
6 · The paper itself

Abstract

The DNA glycosylase NEIL3 has been implicated in DNA repair pathways including the base excision repair and the interstrand cross-link repair pathways via its DNA glycosylase and/or AP lyase activity, which are considered canonical roles of NEIL3 in genome integrity. Compared with the other DNA glycosylases NEIL1 and NEIL2,

Indexed as

DNA-(Apurinic or Apyrimidinic Site) LyaseDNA Breaks, Single-StrandedN-Glycosyl HydrolasesOxidative StressXenopus ProteinsAmino Acid MotifsAnimalsOvumXenopus laevisapex1 protein, XenopusDNA-(Apurinic or Apyrimidinic Site) LyaseN-Glycosyl HydrolasesXenopus ProteinsAPE1APE2DNA damage responseDNA endonucleaseDNA enzymeDNA repairgenome instabilitygenomic instabilityNEIL3ssDNAzinc finger Zf-GRF motif

Identifiers

PMID32817342
PMCPMC7549043
OpenAlexW3049724160

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.