Evidence map›Paper›PMID 32817334›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2020

The Innate Lymphoid System Is a Critical Player in the Manifestation of Mucoinflammatory Airway Disease in Mice.

Brandon W Lewis, Ishita Choudhary, Kshitiz Paudel, Yun Mao, Rahul Sharma, Yong Wang, Jessy S Deshane, Richard C Boucher, Sonika Patial, Yogesh Saini

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Brandon W LewisDepartment of Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803.
Ishita ChoudharyDepartment of Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803.ORCID 0000-0001-8242-3928
Kshitiz PaudelDepartment of Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803.ORCID 0000-0001-7125-8381
Yun MaoDepartment of Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803.ORCID 0000-0003-2768-6308
Rahul SharmaNational Hansen's Disease Program, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803.ORCID 0000-0001-8886-1101
Yong WangDepartment of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294; and.
Jessy S DeshaneDepartment of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294; and.
Richard C BoucherMarsico Lung Institute/University of North Carolina Cystic Fibrosis Center, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.
Sonika PatialDepartment of Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803.ORCID 0000-0002-7373-0835
Yogesh SainiDepartment of Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803; ysaini@lsu.edu.ORCID 0000-0002-8324-2122
Louisiana State University · USUniversity of Alabama at Birmingham · USUniversity of North Carolina at Chapel Hill · US

Funding

The role of adipocyte-driven inflammation and leptin pathway in pulmonary viral infections caused by SARS-CoV-2 and influenza A virusesP20GM130555 · NIGMS · LOUISIANA STATE UNIV A&M COL BATON ROUGE · PI Mariano Carossino · 2019 to 2026
$19.9M
Protein CoreP30GM110760 · NIGMS · LOUISIANA STATE UNIV A&M COL BATON ROUGE · PI KOUSOULAS, KONSTANTIN G · 2014 to 2018
$5.6M
Understanding the role of myeloid cells in ozone-induced airway diseaseR01ES030125 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI SAINI, YOGESH · 2019 to 2024
$2.7M
NIEHS NIH HHS R01 ES030125NIGMS NIH HHS P20 GM130555NIGMS NIH HHS P30 GM110760
6 · The paper itself

Abstract

Innate lymphoid and adaptive immune cells are known to regulate epithelial responses, including mucous cell metaplasia (MCM), but their roles in mucoinflammatory airway diseases, such as cystic fibrosis, remain unknown.

Indexed as

AnimalsCells, CulturedCystic FibrosisDisease Models, AnimalEpithelial CellsEpithelial Sodium ChannelsHomeodomain ProteinsHumansImmunity, InnateInflammationMetaplasiaMiceMice, Inbred C57BLMice, KnockoutMice, TransgenicMucin-5BEpithelial Sodium ChannelsHomeodomain ProteinsMuc5b protein, mouseMucin-5BRAG-1 proteinScnn1b protein, mouse

Identifiers

PMID32817334
PMCPMC7717108
OpenAlexW3070805554

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.