Evidence map›Paper›PMID 32817330›Full record

ArticleInfection and immunity2020

Coxiella burnetii-Infected NK Cells Release Infectious Bacteria by Degranulation.

Svea Matthiesen, Luca Zaeck, Kati Franzke, Rico Jahnke, Charlie Fricke, Michael Mauermeir, Stefan Finke, Anja Lührmann, Michael R Knittler

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06160115 (The Role of Natural Killer Cell Profiling in Predictions of Blood Stream Infection and Antibiotic Resistance in Acute Lymphoblastic Leukemia Patients Post Chemotherapy.), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06160115 unknown statusnot on this mapstarted 2024, after this paper: background citation

The Role of Natural Killer Cell Profiling in Predictions of Blood Stream Infection and Antibiotic Resistance in Acute Lymphoblastic Leukemia Patients Post Chemotherapy.

TypeobservationalSponsorAssiut UniversityRan2024 to 2025Enrolled56ConditionsAcute Lymphoblastic Leukemia, Bloodstream InfectionArmsFlow cytometry
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Svea MatthiesenInstitute of Immunology, Friedrich-Loeffler-Institut, Federal Research Institute of Animal Health, Greifswald, Germany.
Luca ZaeckInstitute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute of Animal Health, Greifswald, Germany.ORCID 0000-0001-7997-493X
Kati FranzkeInstitute of Infectology, Friedrich-Loeffler-Institut, Federal Research Institute of Animal Health, Greifswald, Germany.
Rico JahnkeInstitute of Immunology, Friedrich-Loeffler-Institut, Federal Research Institute of Animal Health, Greifswald, Germany.
Charlie FrickeInstitute of Immunology, Friedrich-Loeffler-Institut, Federal Research Institute of Animal Health, Greifswald, Germany.
Michael MauermeirMicrobiological Institute-Clinical Microbiology, Immunology and Hygiene, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.
Stefan FinkeInstitute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute of Animal Health, Greifswald, Germany.
Anja LührmannMicrobiological Institute-Clinical Microbiology, Immunology and Hygiene, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.
Michael R KnittlerInstitute of Immunology, Friedrich-Loeffler-Institut, Federal Research Institute of Animal Health, Greifswald, Germany michael.knittler@fli.de.ORCID 0000-0002-1603-9861
Friedrich-Loeffler-Institut · DEFriedrich-Alexander-Universität Erlangen-Nürnberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural killer (NK) cells are critically involved in the early immune response against various intracellular pathogens, including

Indexed as

AnimalsCell DegranulationCoxiella burnetiiImmunity, CellularKiller Cells, NaturalMiceQ Fevercell-autonomous immunityChlamydia psittaciCoxiella burnetiiNK cells

Identifiers

PMID32817330
PMCPMC7573450
OpenAlexW3077546941

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.