Evidence map›Paper›PMID 32817097›Full record

ArticleJournal of bacteriology2020

Functions of the BamBCDE Lipoproteins Revealed by Bypass Mutations in BamA.

Elizabeth M Hart, Thomas J Silhavy

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
  2. Article
  3. A mechanism for substrate quality control in outer membrane protein assembly.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Review
  5. Article
  6. A fluorescent reporter and single-turnover kinetics reveal insight into BAM complex function.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Article
  8. Bam complex redefined in Bacteroidota.Nature microbiology · 2025
    Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Elizabeth M HartDepartment of Molecular Biology, Princeton University, Princeton, New Jersey, USA.
Thomas J SilhavyDepartment of Molecular Biology, Princeton University, Princeton, New Jersey, USA tsilhavy@princeton.edu.ORCID 0000-0001-7672-5153
Princeton University · US

Funding

Biogenesis and maintenance of the outer membrane of Gram-negative bacteriaR35GM118024 · NIGMS · PRINCETON UNIVERSITY · PI SILHAVY, THOMAS J. · 2016 to 2025
$8.1M
GENETIC ANALYSIS OF PROTEIN EXPORTR01GM034821 · NIGMS · PRINCETON UNIVERSITY · PI SILHAVY, THOMAS J. · 1985 to 2015
$4.7M
Investigating the mycomembrane protein assembly pathwayK99AI190054 · NIAID · HARVARD MEDICAL SCHOOL · PI Elizabeth Mary Hart · 2025 to 2026
$227k
NIAID NIH HHS K99 AI190054NIGMS NIH HHS R01 GM034821NIGMS NIH HHS R35 GM118024
6 · The paper itself

Abstract

The heteropentomeric β-barrel assembly machine (BAM complex) is responsible for folding and inserting a diverse array of β-barrel outer membrane proteins (OMPs) into the outer membrane (OM) of Gram-negative bacteria. The BAM complex contains two essential proteins, the β-barrel OMP BamA and a lipoprotein BamD, whereas the auxiliary lipoproteins BamBCE are individually nonessential. Here, we identify and characterize three

Indexed as

Bacterial Outer Membrane ProteinsEscherichia coliEscherichia coli ProteinsLipoproteinsMutationProtein FoldingProtein MultimerizationBacterial Outer Membrane ProteinsBamA protein, E coliEscherichia coli ProteinsLipoproteinsBAM complexEscherichia coliGram-negative bacteriaouter membraneouter membrane biogenesis

Identifiers

PMID32817097
PMCPMC7549358
OpenAlexW3079782200

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.