Evidence map›Paper›PMID 32817092›Full record

ArticleJournal of bacteriology2020

Overproduction of a Dominant Mutant of the Conserved Era GTPase Inhibits Cell Division in Escherichia coli.

Xiaomei Zhou, Howard K Peters, Xintian Li, Nina Costantino, Vandana Kumari, Genbin Shi, Chao Tu, Todd A Cameron, Daniel P Haeusser, Daniel E Vega and 3 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of bacteriology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. GTPase Era at the heart of ribosome assembly.Frontiers in molecular biosciences · 2023
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Xiaomei ZhouFrederick National Laboratory for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, Maryland, USA.
Howard K PetersFrederick National Laboratory for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, Maryland, USA.
Xintian LiFrederick National Laboratory for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, Maryland, USA.
Nina CostantinoFrederick National Laboratory for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, Maryland, USA.
Vandana KumariFrederick National Laboratory for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, Maryland, USA.
Genbin ShiFrederick National Laboratory for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, Maryland, USA.
Chao TuFrederick National Laboratory for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, Maryland, USA.
Todd A CameronMicrobiology and Molecular Genetics, McGovern Medical School, Houston, Texas, USA.ORCID 0000-0002-6608-6551
Daniel P HaeusserMicrobiology and Molecular Genetics, McGovern Medical School, Houston, Texas, USA.ORCID 0000-0002-2597-0500
Daniel E VegaMicrobiology and Molecular Genetics, McGovern Medical School, Houston, Texas, USA.
Xinhua JiFrederick National Laboratory for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, Maryland, USA jix@mail.nih.gov william.margolin@uth.tmc.edu.ORCID 0000-0001-6942-1514
William MargolinMicrobiology and Molecular Genetics, McGovern Medical School, Houston, Texas, USA jix@mail.nih.gov william.margolin@uth.tmc.edu.ORCID 0000-0001-6557-7706
Donald L CourtFrederick National Laboratory for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, Maryland, USA.
National Institutes of Health · US

Funding

Targeting and assembly of E. coli division proteinsR01GM061074 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MARGOLIN, WILLIAM · 2000 to 2018
$5.7M
Mechanisms and Regulation of Cell Division in BacteriaR35GM131705 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI WILLIAM MARGOLIN · 2019 to 2026
$3.8M
NCI NIH HHS N01 CO012400NIGMS NIH HHS R01 GM061074NIGMS NIH HHS R35 GM131705
6 · The paper itself

Abstract

Cell growth and division are coordinated, ensuring homeostasis under any given growth condition, with division occurring as cell mass doubles. The signals and controlling circuit(s) between growth and division are not well understood; however, it is known in

Indexed as

Cell Cycle CheckpointsCell DivisionBacterial ProteinsCell Cycle ProteinsCytoskeletal ProteinsEscherichia coliEscherichia coli ProteinsGTP-Binding ProteinsMutant ProteinsRNA-Binding ProteinsBacterial ProteinsCell Cycle ProteinsCytoskeletal Proteinsera protein, E coliEscherichia coli ProteinsFtsZ protein, BacteriaGTP-Binding ProteinsMutant ProteinsRNA-Binding Proteinscell cycle checkpointscytokinesisEraFtsZGTPases

Identifiers

PMID32817092
PMCPMC7549363
OpenAlexW3049195842

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.