Evidence map›Paper›PMID 32817009›Full record

ArticleGenetics2020

Variation Among Biosynthetic Gene Clusters, Secondary Metabolite Profiles, and Cards of Virulence Across

Jacob L Steenwyk, Matthew E Mead, Sonja L Knowles, Huzefa A Raja, Christopher D Roberts, Oliver Bader, Jos Houbraken, Gustavo H Goldman, Nicholas H Oberlies, Antonis Rokas

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 89 citations in OpenAlex.

  1. Opportunistic pathogenicity in fungi can transcend species boundaries.bioRxiv : the preprint server for biology · 2026
    Article
  2. Comparative genome analysis and secondary biosynthetic potential of the Streptomyces microflavus strains isolated from high altitude.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
  3. Article
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  8. Recent developments inMicrobiology and molecular biology reviews : MMBR · 2025
    Review
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  18. Article
  19. A Timeline of Biosynthetic Gene Cluster Discovery inJournal of fungi (Basel, Switzerland) · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 4 countries.

Jacob L SteenwykDepartment of Biological Sciences, Vanderbilt University, Nashville, Tennessee 37235.ORCID 0000-0002-8436-595X
Matthew E Mead *Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee 37235.ORCID 0000-0001-9195-7585
Sonja L Knowles *Department of Chemistry and Biochemistry, University of North Carolina at Greensboro, North Carolina 27402.ORCID 0000-0002-6295-231X
Huzefa A RajaDepartment of Chemistry and Biochemistry, University of North Carolina at Greensboro, North Carolina 27402.ORCID 0000-0002-0824-9463
Christopher D RobertsDepartment of Chemistry and Biochemistry, University of North Carolina at Greensboro, North Carolina 27402.ORCID 0000-0003-0949-1320
Oliver BaderInstitute for Medical Microbiology, University Medical Center Göttingen, 37075, Germany.ORCID 0000-0002-1534-440X
Jos HoubrakenWesterdijk Fungal Biodiversity Institute, 3584 CT Utrecht, The Netherlands.ORCID 0000-0003-4893-4438
Gustavo H GoldmanFaculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, 14040-900 Brazil.ORCID 0000-0002-2986-350X
Nicholas H OberliesDepartment of Chemistry and Biochemistry, University of North Carolina at Greensboro, North Carolina 27402.ORCID 0000-0002-0354-8464
Antonis RokasDepartment of Biological Sciences, Vanderbilt University, Nashville, Tennessee 37235 antonis.rokas@vanderbilt.edu.ORCID 0000-0002-7248-6551
University of North Carolina at Greensboro · USVanderbilt University · USUniversidade de São Paulo · BRUniversitätsmedizin Göttingen · DEWesterdijk Fungal Biodiversity Institute · NL

Funding

Project 3:Isolation Chemistry of Filamentous Fungi and Biological EvaluationP01CA125066 · NCI · OHIO STATE UNIVERSITY · PI Alan Douglas Kinghorn · 2007 to 2026
$27.2M
UNC Greensboro MARC USTAR Engage, Sustain, and PrepareT34GM113860 · NIGMS · UNIVERSITY OF NORTH CAROLINA GREENSBORO · PI GRAVES, JOSEPH LEWIS, HERR, DANIEL J · 2017 to 2021
$1.4M
Deciphering the phenotypic and genomic traits that underlie the evolution of pathogenicity differences among Aspergillus fumigatus and its close relativesR56AI146096 · NIAID · VANDERBILT UNIVERSITY · PI ROKAS, ANTONIS · 2020 to 2020
$592k
Co-culturing to Elicit Chemical Diversity in FungiF31AT010558 · NCCIH · UNIVERSITY OF NORTH CAROLINA GREENSBORO · PI KNOWLES, SONJA LEE · 2019 to 2020
$65k
NCCIH NIH HHS F31 AT010558NCI NIH HHS P01 CA125066NIAID NIH HHS R56 AI146096NIGMS NIH HHS T34 GM113860
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Genes, FungalGenetic VariationSecondary MetabolismAspergillusMultigene FamilyMycotoxinsPhylogenyVirulenceMycotoxinschemodiversitygliotoxinpathogenicitysecondary metabolitesspecialized metabolism

Identifiers

PMID32817009
PMCPMC7536862
OpenAlexW3075913140

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.