Evidence map›Paper›PMID 32816955›Full record

Trial reportBMJ open gastroenterology2020

Endoscopic full-thickness resection and its treatment alternatives in difficult-to-treat lesions of the lower gastrointestinal tract: a cost-effectiveness analysis.

Armin Kuellmer, Juliane Behn, Torsten Beyna, Brigitte Schumacher, Alexander Meining, Helmut Messmann, Horst Neuhaus, David Albers, Michael Birk, Andreas Probst and 6 more

Open access · goldAbstract readClinical TrialComparative StudyMulticenter Study
In one paragraph

Trial report in BMJ open gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Endoscopic Full Thickness Resection Device (FTRDDiagnostics (Basel, Switzerland) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 10 institutions in 1 country.

Armin KuellmerDepartment of Medicine II, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.ORCID 0000-0002-8723-0700
Juliane BehnDepartment of Gastroenterology, Klinikum Ludwigsburg, Ludwigsburg, Baden-Württemberg, Germany.
Torsten BeynaDepartment of Gastroenterology, Evangelisches Krankenhaus Düsseldorf, Dusseldorf, Nordrhein-Westfalen, Germany.
Brigitte SchumacherDepartment of Internal Medicine and Gastroenterology, Elisabeth Hospital, Essen, Nordrhein-Westfalen, Germany.
Alexander MeiningDepartment of Medicine II, Interventional and Experimental Endoscopy (InExEn), University Hospital Wurzburg, Wurzburg, Bayern, Germany.
Helmut MessmannDepartment of Gastroenterology, University Hospital Augsburg, Augsburg, Bayern, Germany.
Horst NeuhausDepartment of Gastroenterology, Evangelisches Krankenhaus Düsseldorf, Dusseldorf, Nordrhein-Westfalen, Germany.
David AlbersDepartment of Internal Medicine and Gastroenterology, Elisabeth Hospital, Essen, Nordrhein-Westfalen, Germany.
Michael BirkDepartment of Gastroenterology, University Hospital Ulm, Ulm, Baden-Württemberg, Germany.
Andreas ProbstDepartment of Gastroenterology, University Hospital Augsburg, Augsburg, Bayern, Germany.
Martin FaehndrichDepartment of Gastroenterology, Klinikum Dortmund, Dortmund, Nordrhein-Westfalen, Germany.
Thomas FrielingDepartment of Gastroenterology, HELIOS Klinikum Krefeld, Krefeld, Nordrhein-Westfalen, Germany.
Martin GoetzDepartment of Gastroenterology/Oncology, Klinikum Sindelfingen-Böblingen, Sindelfingen, Baden-Württemberg, Germany.
Robert ThimmeDepartment of Medicine II, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Karel CacaDepartment of Gastroenterology, Klinikum Ludwigsburg, Ludwigsburg, Baden-Württemberg, Germany.
Arthur SchmidtDepartment of Medicine II, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany Arthur.schmidt@uniklinik-freiburg.de.
University of Freiburg · DEElisabeth-Krankenhaus Essen · DEEvangelisches Krankenhaus Düsseldorf · DEKlinikum Ludwigsburg · DEUniversity Hospital Augsburg · DEHelios Klinikum Krefeld · DEKlinikum Dortmund · DEKlinikum Sindelfingen-Böblingen · DEUniversitätsklinikum Würzburg · DEUniversity Hospital Ulm · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveEndoscopic full-thickness resection (EFTR) has shown efficacy and safety in the colorectum. The aim of this analysis was to investigate whether EFTR is cost-effective in comparison with surgical and endoscopic treatment alternatives.

designReal data from the study cohort of the prospective, single-arm WALL RESECT study were used. A simulated comparison arm was created based on a survey that included suggested treatment alternatives to EFTR of the respective lesions. Treatment costs and reimbursement were calculated in euro according to the coding rules of 2017 and 2019 (EFTR). R0 resection rate was used as a measure of effectiveness. To assess cost-effectiveness, the average cost-effectiveness ratio (ACER) and the incremental cost-effectiveness ratio (ICER) were determined. Calculations were made both from the perspective of the care provider as well as of the payer.

resultsThe cost per case was €2852.20 for the EFTR group, €1712 for the standard endoscopic resection (SER) group, €8895 for the surgical resection group and €5828 for the pooled alternative treatment to EFTR. From the perspective of the care provider, the ACER (mean cost per R0 resection) was €3708.98 for EFTR, €3115.10 for SER, €8924.05 for surgical treatment and €7169.30 for all pooled and weighted alternatives to EFTR. The ICER (additional cost per R0 resection compared with EFTR) was €5196.47 for SER, €26 533.13 for surgical resection and €67 768.62 for the pooled rate of alternatives. Results from the perspective of the payer were similar.

conclusionEFTR is cost-effective in comparison with surgical and endoscopic treatment alternatives in the colorectum.

Indexed as

Colorectal NeoplasmsCost-Benefit AnalysisEndoscopy, GastrointestinalHumansLower Gastrointestinal TractProspective StudiesQuality-Adjusted Life YearsSafetySurveys and QuestionnairesTreatment Outcomecolorectal adenomascolorectal cancercost-effectivenessendoscopic polypectomy

Identifiers

PMID32816955
PMCPMC7437695
OpenAlexW3071228930

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.