Evidence map›Paper›PMID 32816816›Full record

SynthesisBMJ (Clinical research ed.)2020

Self-management interventions to reduce healthcare use and improve quality of life among patients with asthma: systematic review and network meta-analysis.

Alexander Hodkinson, Peter Bower, Christos Grigoroglou, Salwa S Zghebi, Hilary Pinnock, Evangelos Kontopantelis, Maria Panagioti

Erratum issued Registry-linked trialAbstract readSystematic ReviewNetwork Meta-Analysis
In one paragraph

Synthesis in BMJ (Clinical research ed.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT07061587 (Developing A Gout Action Plan in Primary Care Setting in Singapore), which is not on this map. Cited by 63 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07061587 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Developing A Gout Action Plan in Primary Care Setting in Singapore

TypeinterventionalSponsorSingHealth PolyclinicsRan2025 to 2027Enrolled72ConditionsGout, Hyperuricemia, Gout Flare, Gout ChronicArmsGout action plan
3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Delivery of supported self-management in remote asthma reviews: A systematic rapid realist review.Health expectations : an international journal of public participation in health care and health policy · 2022
    Pooled it
  6. Trial
  7. Trial
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  13. Review
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  15. Observational
  16. Article
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  19. Article
  20. Asthma: Biomedical and Psychobiological Perspectives.Biopsychosocial science and medicine · 2025
    Review

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Alexander HodkinsonNational Institute for Health Research School for Primary Care Research, Manchester Academic Health Science Centre, University of Manchester, Manchester M13 9PL, UK alexander.hodkinson@manchester.ac.uk.ORCID 0000-0003-2063-0977
Peter BowerNational Institute for Health Research School for Primary Care Research, Manchester Academic Health Science Centre, University of Manchester, Manchester M13 9PL, UK.
Christos GrigoroglouNational Institute for Health Research School for Primary Care Research, Manchester Academic Health Science Centre, University of Manchester, Manchester M13 9PL, UK.
Salwa S ZghebiNational Institute for Health Research School for Primary Care Research, Manchester Academic Health Science Centre, University of Manchester, Manchester M13 9PL, UK.
Hilary PinnockAsthma UK Centre for Applied Research, Usher Institute, University of Edinburgh, Edinburgh, UK.
Evangelos KontopantelisNational Institute for Health Research School for Primary Care Research, Manchester Academic Health Science Centre, University of Manchester, Manchester M13 9PL, UK.
Maria PanagiotiNational Institute for Health Research School for Primary Care Research, Manchester Academic Health Science Centre, University of Manchester, Manchester M13 9PL, UK.

Funding

Department of Health RP-PG-1016-20008
6 · The paper itself

Abstract

objectiveTo compare the different self-management models (multidisciplinary case management, regularly supported self-management, and minimally supported self-management) and self-monitoring models against usual care and education to determine which are most effective at reducing healthcare use and improving quality of life in asthma.

designSystematic review and network meta-analysis. DATA SOURCES: Medline, the Cochrane Library, CINAHL, EconLit, Embase, Health Economics Evaluations Database, NHS Economic Evaluation Database, PsycINFO, and ClinicalTrials.gov from January 2000 to April 2019. REVIEW

methodsRandomised controlled trials involving the different self-management models for asthma were included. The primary outcomes were healthcare use (hospital admission or emergency visit) and quality of life. Summary standardised mean differences (SMDs) and 95% credible intervals were estimated using bayesian network meta-analysis with random effects. Heterogeneity and publication bias were assessed.

resultsFrom 1178 citations, 105 trials comprising 27 767 participants were included. In terms of healthcare use, both multidisciplinary case management (SMD -0.18, 95% credible interval -0.32 to -0.05) and regularly supported self-management (-0.30, -0.46 to -0.15) were significantly better than usual care. For quality of life, only regularly supported self-management (SMD 0.54, 0.11 to 0.96) showed a statistically significant benefit compared with usual care. For trials including adolescents/children (age 5-18 years), only regularly supported self-management showed statistically significant benefits (healthcare use: SMD -0.21, -0.40 to -0.03; quality of life: 0.23, 0.03 to 0.48). Multidisciplinary case management (SMD -0.32, -0.50 to -0.16) and regularly supported self-management (-0.32, -0.53 to -0.11) were most effective at reducing healthcare use in patients with symptoms of severe asthma at baseline.

conclusionsThis network meta-analysis indicates that regularly supported self-management reduces the use of healthcare resources and improves quality of life across all levels of asthma severity. Future healthcare investments should provide support that offer reviews totalling at least two hours to establish self-management skills, reserving multidisciplinary case management for patients with complex disease. SYSTEMATIC REVIEW REGISTRATION: PROSPERO number CRD42019121350.

Indexed as

Quality of LifeSelf-ManagementAsthmaHumansPatient Acceptance of Health Care

Identifiers

PMID32816816
PMCPMC7431958

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.