Evidence map›Paper›PMID 32816599›Full record

ArticleCell cycle (Georgetown, Tex.)2020

TRIM71 binds to IMP1 and is capable of positive and negative regulation of target RNAs.

Daniel J Foster, Hao-Ming Chang, Jeffrey R Haswell, Richard I Gregory, Frank J Slack

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell cycle (Georgetown, Tex.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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  6. Frontiers in cell and developmental biology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Daniel J FosterHMS Initiative for RNA Medicine, Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School , Boston, MA, USA.ORCID 0000-0002-2466-9484
Hao-Ming ChangStem Cell Program, Boston Children's Hospital, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Harvard Stem Cell Institute , Boston, MA, USA.
Jeffrey R HaswellHMS Initiative for RNA Medicine, Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School , Boston, MA, USA.
Richard I GregoryStem Cell Program, Boston Children's Hospital, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Harvard Stem Cell Institute , Boston, MA, USA.
Frank J SlackHMS Initiative for RNA Medicine, Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School , Boston, MA, USA.ORCID 0000-0001-8263-0409
Beth Israel Deaconess Medical Center · USBoston Children's Hospital · US

Funding

Precision microRNA medicine in cancerR35CA232105 · NCI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI SLACK, FRANK J. · 2019 to 2025
$7.2M
NCI NIH HHS R35 CA232105
6 · The paper itself

Abstract

TRIM71 is an important RNA-binding protein in development and disease, yet its direct targets have not been investigated globally. Here we describe a number of disease and developmentally-relevant TRIM71 RNA targets such as the

Indexed as

Carcinoma, HepatocellularCell ProliferationCellular SenescenceGene Expression Regulation, NeoplasticHep G2 CellsHumansLiver NeoplasmsPoint MutationProtein BindingProtein Interaction Domains and MotifsRNA-Binding ProteinsRNA, NeoplasmRNA StabilitySequence DeletionTripartite Motif ProteinsUbiquitin-Protein LigasesIGF2BP1 protein, humanRNA-Binding ProteinsRNA, NeoplasmTRIM71 protein, humanTripartite Motif ProteinsUbiquitin-Protein LigasescrosslinkingIGF2BP1IMP1liver cancerRIP-seqRNABPTRIM71

Identifiers

PMID32816599
PMCPMC7513864
OpenAlexW3081503253

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.