Evidence map›Paper›PMID 32816535›Full record

SynthesisThe American journal of sports medicine2021

A Word of Caution for Future Studies in Patellofemoral Pain: A Systematic Review With Meta-analysis.

Camila Grant, Cameron N Fick, Judith Welsh, Jenny McConnell, Frances T Sheehan

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in The American journal of sports medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Patellar Tracking: An Old Problem with New Insights.Radiographics : a review publication of the Radiological Society of North America, Inc · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Camila GrantDepartment of Rehabilitation Medicine, National Institutes of Health, Bethesda, Maryland, USA.
Cameron N FickDepartment of Rehabilitation Medicine, National Institutes of Health, Bethesda, Maryland, USA.
Judith WelshNational Institutes of Health Library, Office of Research Services, National Institutes of Health, Bethesda, Maryland, USA.
Jenny McConnellCentre for Health Exercise and Sports Medicine, University of Melbourne, Melbourne, Australia.
Frances T SheehanDepartment of Rehabilitation Medicine, National Institutes of Health, Bethesda, Maryland, USA.

Funding

Virtual Functional AnatomyZIACL060062 · CLC · CLINICAL CENTER · PI SHEEHAN, FRANCES T · 2009 to 2025
$0k
Intramural NIH HHS Z99 CL999999
6 · The paper itself

Abstract

backgroundPatellar maltracking is widely accepted as an underlying mechanism of patellofemoral pain. However, methodological differences in the literature hinder our ability to generate a universal quantitative definition of pathological patellofemoral kinematics (patellar maltracking) in patellofemoral pain, leaving us unable to determine the cause of patellofemoral pain. PURPOSE: To systematically review the literature to provide evidence regarding the influence of confounding variables on patellofemoral kinematics. STUDY

designSystematic review and random effects meta-analysis of control-case studies.

methodsA literature search of case-control studies that evaluated patellofemoral kinematics at or near full extension and were written in English was conducted using Embase, PubMed, Scopus, and Web of Science up to September 2019. Cases were defined as patients with patellofemoral pain. Studies were eliminated if they lacked quantitative findings; had a primary aim to assess therapy efficacy; or included participants with osteoarthritis and/or previous trauma, pathology, or surgery. A quality assessment checklist was employed to evaluate each study. Meta-analyses were conducted to determine the influence of confounding variables on measures of patellofemoral kinematics.

resultsForty studies met the selection criteria, with quality scores ranging from 13% to 81%. Patient characteristics, data acquisition, and measurement methods were the primary sources of methodological variability. Active quadriceps significantly increased lateral shift (standardized mean difference [SMD]

conclusionThis review exposed large methodological variability across the literature, which not only hinders the generalization of results, but ultimately mitigates our understanding of the underlying mechanism of patellofemoral pain. Although our meta-analyses support the diagnostic value of maltracking in patellofemoral pain, the numerous distinct methods for measuring maltracking and the limited control for cofounding variables across the literature prohibit defining a single quantitative profile. Compliance with specific standards for anatomic and outcome measures must be addressed by the scientific and clinical community to establish methodological uniformity in this field.

Indexed as

Biomechanical PhenomenaCase-Control StudiesHumansJoint DislocationsPatellaPatellofemoral JointPatellofemoral Pain SyndromeQuadriceps Muscledislocationkinematicsmaltrackingpatellofemoral joint

Identifiers

PMID32816535
PMCPMC9906796

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.