ReviewCurrent reviews in musculoskeletal medicine2020
Optimizing the Spinal Interbody Implant: Current Advances in Material Modification and Surface Treatment Technologies.
Review in Current reviews in musculoskeletal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed.
- Outcomes comparison between novel hydroxyapatite enhanced polyetheretherketone and titanium implants after anterior lumbar interbody fusion.Journal of spine surgery (Hong Kong) · 2026Article
- Section on innovative spine research and novel technologies: fusion cage design, materials, and coatings: Science versus hype.North American Spine Society journal · 2025Article
- Advancements in biomaterials and bioactive solutions for lumbar spine fusion cages: Current trends and future perspectives.Bioactive materials · 2025Review
- Effect of Sandblasting Process on 3D Printed Intervertebral Cage.3D printing and additive manufacturing · 2025Article
- Radiographic and Clinical Comparison of Polyetheretherketone Versus 3D-Printed Titanium Cages in Lumbar Interbody Fusion-A Single Institution's Experience.Journal of clinical medicine · 2025Article
- Loss of Mass and Surface Topography in 3-Dimensional-Printed Solid Titanium Cages Upon Impaction: An In Vitro Model.Neurospine · 2025Article
- Three dimensional-printed artificial disc replacement for single-level cervical spondylosis: a cohort study.International orthopaedics · 2025Article
- First clinical experience with posterior lumbar interbody fusion using a thermal-sprayed silver-containing hydroxyapatite-coated cage.Journal of orthopaedic surgery and research · 2023Article
- The Clinical Use of Osteobiologic and Metallic Biomaterials in Orthopedic Surgery: The Present and the Future.Materials (Basel, Switzerland) · 2023Review
- Review
- The effect of expandable versus static lordotic interbody implants in minimally invasive spine surgery: patient reported outcomes, sagittal alignment, and restoration of disc height and foraminal height.Journal of spine surgery (Hong Kong) · 2023Article
- A novel nanohydroxyapatite/polyamide-66 cage for reducing the subsidence rate after single-level anterior cervical discectomy and fusion: a comparative study of 7-year follow-up.Journal of orthopaedic surgery and research · 2023Article
- Corrosion Resistance of 3D Printed Ti6Al4V Gyroid Lattices with Varying Porosity.Materials (Basel, Switzerland) · 2022Article
- Evolution of Bioactive Implants in Lateral Interbody Fusion.International journal of spine surgery · 2022Article
- Biomaterials for Interbody Fusion in Bone Tissue Engineering.Frontiers in bioengineering and biotechnology · 2022Review
- Endplate volumetric bone mineral density biomechanically matched interbody cage.Frontiers in bioengineering and biotechnology · 2022Article
- Can activated titanium interbody cages accelerate or enhance spinal fusion? a review of the literature and a design for clinical trials.Journal of materials science. Materials in medicine · 2021Review
- Sustainable Surface Modification of Polyetheretherketone (PEEK) Implants by Hydroxyapatite/Silica Coating-An In Vivo Animal Study.Materials (Basel, Switzerland) · 2021Article
- Single-Level Cervical Disc Replacement Using a PEEK-on-Ceramic Implant: Results of a Multicenter FDA IDE Trial With 24-Month Follow-up.International journal of spine surgery · 2021Article
- Review on Development and Dental Applications of Polyetheretherketone-Based Biomaterials and Restorations.Materials (Basel, Switzerland) · 2021Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewInterbody implants allow for fusion of the anterior column of the spine between vertebral body endplates. As rates of spinal fusion surgery have increased over the past several years, significant research has been devoted to optimizing both the mechanical and biologic properties of the interbody implant in order to promote bony fusion. The first interbody implants used decades ago were fashioned from cortical autograft. Currently, titanium alloy and polyetheretherketone (PEEK) are the most widely used and studied materials for this purpose. This review focuses on recent innovations in material modification and surface treatment techniques for both titanium and PEEK implants to maximize fusion rates in spinal surgery. RECENT
findingsTitanium has an elastic modulus much higher than native bone and however has better osseointegrative properties than PEEK. PEEK, however, has an elastic modulus closer to that of bone without any of the advantageous biologic properties that titanium has. Increasing porosity and surface roughness of titanium implants have been shown to improve the mechanical properties of titanium implants, while the biologic properties of PEEK have been enhanced using surface coating technology, either with titanium or with hydroxyapatite (HA). Techniques such as increasing porosity, surface roughening, and surface coating are just some of the recent innovations aimed at optimizing both mechanical and biologic properties of interbody implants to promote spinal fusion. The future of interbody implant design will rely on continued improvements of PEEK and titanium implants as well as exploring new implant materials altogether.
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