ArticleBiological trace element research2021
The Effects of Metal Exposures on Charlson Comorbidity Index Using Zero-Inflated Negative Binomial Regression Model: NHANES 2011-2016.
Article in Biological trace element research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 26 citations in OpenAlex.
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- Association of inflammation and nutrition-based indicators with chronic obstructive pulmonary disease and mortality.Journal of health, population, and nutrition · 2024Article
- Dietary patterns among U.S. food insecure cancer survivors and the risk of mortality: NHANES 1999-2018.Cancer causes & control : CCC · 2024Article
- Association between serum neurofilament light chain and periodontitis.Clinical oral investigations · 2024Article
- Heterogeneity of aging and mortality risk among individuals with hypertension: Insights from phenotypic age and phenotypic age acceleration.The journal of nutrition, health & aging · 2024Article
- Associations of the Charlson comorbidity index with depression and mortality among the U.S. adults.Frontiers in public health · 2024Article
- Application of marginalized zero-inflated models when mediators have excess zeroes.Statistical methods in medical research · 2024Article
- Associations of telomere length with risk of mortality from influenza and pneumonia in US adults: a prospective cohort study of NHANES 1999-2002.Aging clinical and experimental research · 2023Article
- Estimated pulse wave velocity is associated with all-cause mortality and cardiovascular mortality among adults with diabetes.Frontiers in cardiovascular medicine · 2023Article
- Nocturnal sleep duration and bone mineral density: a cross-sectional study of the National Health and Nutrition Examination Survey (NHANES) 2007-2014.BMC endocrine disorders · 2022Article
- Empirical Dietary Patterns Associated with Food Insecurity in U.S. Cancer Survivors: NHANES 1999-2018.International journal of environmental research and public health · 2022Article
- Analysis of zero inflated dichotomous variables from a Bayesian perspective: application to occupational health.BMC medical research methodology · 2021Article
- Exploring age-related physical and cognitive decline in a nationally representative sample of US women.Women's health (London, England)Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWith the rising incidence of chronic diseases, and the increase of aging population has led to multimorbidity a serious public health problem. The aim of this study was to explore the association between metal exposures and Charlson comorbidity index (CCI), which will provide valuable information for improving quality of life and reducing mortality.
methodsThe study sample consists of three continuous cycles (2011-2016) of the National Health and Nutrition Examination Survey (NHANES), and 4901 eligible subjects were included in the study. Zero-inflated negative binomial (ZINB) model was utilized to investigate the effects in metal exposures on CCI, which includes spot urine (arsenic, mercury, and cadmium), whole blood (manganese, selenium, and lead), and serum (copper and zinc).
resultsIn count part (CCI ≥ 0), holding other variables constant, the expected change in CCI for a one-unit increase in blood selenium is 0.997 (RR = 0.997, p = 0.017). In logit part (CCI = 0), the log odds of having CCI equals zero would increase by 0.659, 1.073, and 0.963 for every additional urinary cadmium (OR = 0.659, p = 0.007), blood lead (OR = 1.073, p = 0.023), blood manganese (OR = 0.963, p = 0.025), respectively.
conclusionsOur findings indicated that cadmium and manganese were likely to increase mortality. Inversely, selenium and lead might be positive on people's health. The findings may be extremely essential for preventing diseases and improving life quality.
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