ArticleLangenbeck's archives of surgery2020
Definition and severity grading of postoperative lymphatic leakage following inguinal lymph node dissection.
Article in Langenbeck's archives of surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 21 citations in OpenAlex.
- Radiotherapy for postoperative groin lymphatic fistulas: A systematic review of clinical outcomes and treatment planning.Clinical and translational radiation oncology · 2026Review
- Intraperitoneal OK-432 infusion for postoperative lymphatic leakage in gynecologic tumors.Gynecologic oncology reports · 2026Article
- Article
- Reconstructing cerebral lymphatic clearance: an emerging target in the Alzheimer's disease therapeutic pipeline.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Review
- Occurrence, Definition and Risk Factors Related to Groin Wound Complications Following Open Vascular Surgeries.International wound journal · 2026Article
- Therapy-refractory lymphatic fistulas following complete lymph node dissection in malignant melanoma: local radiotherapy as an effective therapeutic modality to avoid cancer treatment delay.Langenbeck's archives of surgery · 2026Article
- A case of groin lymphorrhea after a leadless pacemaker implantation.HeartRhythm case reports · 2025Article
- Wound Healing Complication in Radio-Treated Limb Soft Tissue Sarcoma Patients: A Single Referral Centre Experience.International wound journal · 2025Review
- Postoperative lymphatic leakage following laparoscopic totally extraperitoneal inguinal hernia repair: the first case report and review of the literature.Hernia : the journal of hernias and abdominal wall surgery · 2025Review
- Risk factors for lymphatic leakage following radical cystectomy and pelvic lymph node dissection in patients with muscle-invasive bladder cancer.World journal of surgical oncology · 2025Article
- ICG mapping of postoperative lymphatic leakage in the groin: a video article and literature review.Facts, views & vision in ObGyn · 2024Article
- Complications and adverse events in lymphadenectomy of the inguinal area: worldwide expert consensus.BJS open · 2024Article
- Lymph node metastasis in cancer progression: molecular mechanisms, clinical significance and therapeutic interventions.Signal transduction and targeted therapy · 2023Review
- Postoperative drainage management and wound complications following resection of lower limb soft tissue tumors: a retrospective cohort study.Langenbeck's archives of surgery · 2023Article
- Perioperative and oncologic outcomes of laparoscopic versus open liver resection for combined hepatocellular-cholangiocarcinoma: a propensity score matching analysis.Surgical endoscopy · 2023Article
- Lymphatic Function of the Lower Limb after Groin Dissection for Vulvar Cancer and Reconstruction with Lymphatic SCIP Flap.Cancers · 2022Article
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeLymphatic complications occur frequently after radical inguinal lymph node dissection (RILND). The incidence of lymphatic leakage varies considerably among different studies due to the lack of a consistent definition. The aim of the present study is to propose a standardized definition and grading of different types of lymphatic leakage after groin dissection.
methodsA bicentric retrospective analysis of 82 patients who had undergone RILND was conducted. A classification of postoperative lymphatic leakage was developed on the basis of the daily drainage output, any necessary postoperative interventions and reoperations, and any delay in adjuvant treatment.
resultsIn the majority of cases, RILND was performed in patients with inguinal metastases of malignant melanoma (n = 71). Reinterventions were necessary in 15% of the patients and reoperations in 32%. A new classification of postoperative lymphatic leakage was developed. According to this definition, grade A lymphatic leakage (continued secretion of lymphatic fluid from the surgical drains without further complications) occurred in 13% of the patients, grade B lymphatic leakage (persistent drainage for more than 10 postoperative days or the occurrence of a seroma after the initial removal of the drain that requires an intervention) in 28%, and grade C lymphatic leakage (causing a reoperation or a subsequent conflict with medical measures) in 33%. The drainage volume on the second postoperative day was a suitable predictor for a complicated lymphatic leakage (grades B and C) with a cutoff of 110 ml.
conclusionThe proposed definition is clinically relevant, is easy to employ, and may serve as the definition of a standardized endpoint for the assessment of lymphatic morbidity after RILND in future studies.
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