Evidence map›Paper›PMID 32816101›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2020

Influence of oral anticoagulation on success rates and risk of bleeding events after iStent inject implantation combined with phacoemulsification.

Randolf A Widder, Alexandra Lappas, Corinna Rennings, Matthias Hild, Gernot F Roessler, Thomas S Dietlein

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Safety of gonioscopy-assisted transluminal trabeculotomy without antithrombotic discontinuation versus no antithrombotic therapy: a large cohort study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
  2. Visual Function After Schlemm's Canal-Based MIGS.Journal of clinical medicine · 2025
    Review
  3. Article
  4. [Anticoagulation and platelet aggregation inhibition : What needs to be considered in the ophthalmological practice].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2021
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Randolf A WidderDepartment of Ophthalmology, St. Martinus-Krankenhaus Düsseldorf, Gladbacher Strasse 26, 40219, Düsseldorf, Germany. r.widder@martinus-duesseldorf.de.ORCID http://orcid.org/0000-0001-7487-1501
Alexandra LappasCenter of Ophthalmology, University of Cologne, Kerpener Strasse 62, 50937, Köln, Germany.
Corinna RenningsDepartment of Ophthalmology, St. Martinus-Krankenhaus Düsseldorf, Gladbacher Strasse 26, 40219, Düsseldorf, Germany.
Matthias HildDepartment of Ophthalmology, St. Martinus-Krankenhaus Düsseldorf, Gladbacher Strasse 26, 40219, Düsseldorf, Germany.
Gernot F RoesslerDepartment of Ophthalmology, St. Martinus-Krankenhaus Düsseldorf, Gladbacher Strasse 26, 40219, Düsseldorf, Germany.
Thomas S DietleinCenter of Ophthalmology, University of Cologne, Kerpener Strasse 62, 50937, Köln, Germany.
Martin-Luther-Krankenhaus · DEUniversity of Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe conducted a retrospective study to evaluate the intraocular pressure (IOP) lowering effect, the success rates, and the risk of bleeding events of patients receiving an iStent inject combined with phacoemulsification under anticoagulation therapy compared with a matched control group.

methodsIn this retrospective study, sixty-four eyes underwent an iStent inject implantation combined with phacoemulsification at two centers. Thirty-two eyes received surgery while under anticoagulation therapy, and another thirty-two eyes served as a control group matched for visual acuity, IOP, and medication score. Success was defined as criteria A and B (IOP < 18/21 mmHg, > 20% IOP reduction, no resurgery) and criteria C (IOP ≤ 15 mmHg, IOP reduction ≥ 40%, no resurgery). The clinical goal of the study was to determine the difference between the study and control groups with respect to IOP, medication score, and the frequency of intraoperative and postoperative bleeding events.

resultsAfter a mean follow-up time of 1 year, the IOP lowered 28% from 20.1 ± 4.8 to 14.5 ± 3.7 mmHg in the group of 64 eyes. The medication score lowered 38% from 2.1 ± 1.1 to 1.3 ± 1.2. The two groups with and without anticoagulant agents did not significantly differ in postoperative IOP, medication score, success rates, or number of bleeding events.

conclusionWe conclude that in cataract surgery combined with the iStent inject a discontinuation of anticoagulant agents might not be necessary. It might be a good option in glaucoma surgery when anticoagulation treatment should not be interrupted and the target pressure is not very low.

Indexed as

Glaucoma, Open-AnglePhacoemulsificationAnticoagulantsHumansIntraocular PressureRetrospective StudiesStentsAnticoagulantsAnticoagulation therapyGlaucomaGlaucoma surgeryiStentMIGS

Identifiers

PMID32816101
PMCPMC7584552
OpenAlexW4232108375

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.