Evidence map›Paper›PMID 32816067›Full record

ArticleJournal of materials science. Materials in medicine2020

Three dimensional printed bioglass/gelatin/alginate composite scaffolds with promoted mechanical strength, biomineralization, cell responses and osteogenesis.

Qing Ye, Ying Zhang, Kun Dai, Xiaofeng Chen, Hannah Mae Read, Lei Zeng, Fei Hang

Abstract read
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In one paragraph

Article in Journal of materials science. Materials in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qing YeSchool of Material Science and Engineering, South China University of Technology, 510641, Guangzhou, PR China.
Ying ZhangNational Engineering Research Center for Tissue Restoration and Reconstruction, South China University of Technology, 510006, Guangzhou, PR China.
Kun DaiNational Engineering Research Center for Tissue Restoration and Reconstruction, South China University of Technology, 510006, Guangzhou, PR China.
Xiaofeng ChenKey Laboratory of Biomedical Engineering of Guangdong Province, South China University of Technology, 510006, Guangzhou, PR China.
Hannah Mae ReadSchool of Engineering, University of Glasgow, Scotland, G11 6BZ, UK.
Lei ZengNational Engineering Research Center for Tissue Restoration and Reconstruction, South China University of Technology, 510006, Guangzhou, PR China. happy-zl@163.com.
Fei HangSchool of Material Science and Engineering, South China University of Technology, 510641, Guangzhou, PR China. hfei@scut.edu.cn.

Funding

the National Nature Science Foundation of China 31500762
6 · The paper itself

Abstract

In this study, porous bioglass/gelatin/alginate bone tissue engineering scaffolds were fabricated by three-dimensional printing. The compressive strength and in vitro biomineralization properties of the bioglass-gelatin-alginate scaffolds (BG/Gel/SA scaffolds) were significantly improved with the increase of bioglass content until 30% weight percentage followed by a rapid decline in strength. In addition, the cells attach and spread on the BG/Gel/SA scaffolds surfaces represents good adhesion and biocompatibility. Furthermore, the cells (rat bone marrow mesenchymal stem cells, mBMSCs) proliferation and osteogenic differentiation on the BG/Gel/SA scaffolds were also promoted with the increase of bioglass content. Overall, the adding of bioglass in Gel/SA scaffolds promotes mechanical strength and in vitro osteogenic properties and the 30 BG scaffold (30%wt BG) has potential applications in bone tissue engineering and bone regenerative repair because of good compressive strength, biocompatibility, and in vitro osteogenesis.

Indexed as

BiomineralizationPrinting, Three-DimensionalAlginatesAnimalsBiocompatible MaterialsBone and BonesBone RegenerationCell AdhesionCell DifferentiationCell ProliferationCells, CulturedCell SurvivalCeramicsCompressive StrengthGelatinHydrogelsAlginatesBiocompatible MaterialsBioglassGelatinHydrogels

Identifiers

PMID32816067

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.