Evidence map›Paper›PMID 32815632›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2020

Physical activity is associated with lower arterial stiffness in normal-weight postmenopausal women.

Kimon Stamatelopoulos, Nikolaos Tsoltos, Eleni Armeni, Stavroula A Paschou, Areti Augoulea, Georgios Kaparos, Demetrios Rizos, Iliana Karagouni, Dimitris Delialis, Sophia Ioannou and 3 more

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In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.

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  15. The cardiometabolic benefits of exercise in postmenopausal women.Journal of clinical hypertension (Greenwich, Conn.) · 2020
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Kimon StamatelopoulosVascular Laboratory, Department of Therapeutics, Alexandra Hospital, National and Kapodistrian University of Athens, Athens, Greece.ORCID 0000-0001-6444-8734
Nikolaos TsoltosSecond Department of Obstetrics and Gynecology, Aretaieio Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Eleni ArmeniSecond Department of Obstetrics and Gynecology, Aretaieio Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Stavroula A PaschouSecond Department of Obstetrics and Gynecology, Aretaieio Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Areti AugouleaSecond Department of Obstetrics and Gynecology, Aretaieio Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Georgios KaparosHormonal and Biochemical Laboratory, Aretaieio Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Demetrios RizosHormonal and Biochemical Laboratory, Aretaieio Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Iliana KaragouniSecond Department of Obstetrics and Gynecology, Aretaieio Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Dimitris DelialisVascular Laboratory, Department of Therapeutics, Alexandra Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Sophia IoannouVascular Laboratory, Department of Therapeutics, Alexandra Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Michail ApostolakisSecond Department of Obstetrics and Gynecology, Aretaieio Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Evangelos MakrakisThird Department of Obstetrics and Gynecology, Aretaieio Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Irene LambrinoudakiSecond Department of Obstetrics and Gynecology, Aretaieio Hospital, National and Kapodistrian University of Athens, Athens, Greece.ORCID 0000-0003-1488-2668
National and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The impact of physical exercise, as preventative measure, to control the progression of cardiovascular disease in midlife remains under investigation. We aimed to investigate the effect of different levels of intensity of physical activity on metabolic and vascular profile in healthy postmenopausal women. A total of 625 healthy postmenopausal women (mean age 57.7 ± 7.6 years) were evaluated using the short IPAQ questionnaire for quantification of physical activity. The energy expenditure was estimated in metabolic equivalent of energy (MET) hours per week. Pulse wave velocity (PWV) was measured as an index of arterial stiffness. Intima-media thickness of both right and left common carotid artery, carotid bulb and internal carotid artery, and combined carotid IMT were also assessed by non-invasive and well-validated methods. Mean values of PWV decreased linearly with increasing intensity of physical activity (classes of physical activity: sedentary vs walking vs moderate vs vigorous activity: 9.07 ± 1.22 m/s vs 9.12 ± 1.72 m/s vs 8.47 ± 1.31m/s vs 7.94 ± 0.40 m/s, ANOVA P for linear trend .003). In non-obese postmenopausal women, PWV values associated with: (a) the total number of METs (b-coefficient = -0.261, P = .002) as well as with SBP; (b) or with the number of moderate METs (b-coefficient = -0.192, P = .025) as well as with age and SBP. No significant associations were observed between the intensity of physical exercise and arterial stiffness in the overweight-obese group. Physical activity is negatively associated with arterial stiffness in postmenopausal women with normal weight. This association was not observed in overweight or obese women.

Indexed as

ExerciseVascular StiffnessAgedCarotid Intima-Media ThicknessFemaleHumansHypertensionMiddle AgedPostmenopausePulse Wave Analysisarterial stiffnessmenopauseobesityphysical exercise

Identifiers

PMID32815632
PMCPMC8029682
OpenAlexW3081223357

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.