Evidence map›Paper›PMID 32815622›Full record

ArticleInfluenza and other respiratory viruses2021

Cepheid Xpert

Nasir Wabe, Robert Lindeman, Jeffrey J Post, William Rawlinson, Melissa Miao, Johanna I Westbrook, Andrew Georgiou

Abstract read
In one paragraph

Article in Influenza and other respiratory viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Cepheid XpertInfluenza and other respiratory viruses · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nasir WabeCentre for Health Systems and Safety Research, Australian Institute of Health Innovation, Macquarie University, North Ryde, NSW, Australia.ORCID 0000-0002-9740-6319
Robert LindemanNSW Health Pathology, Chatswood, NSW, Australia.
Jeffrey J PostDepartment of Infectious Diseases, Prince of Wales Hospital and Community Health Services, Randwick, NSW, Australia.
William RawlinsonNSW Health Pathology Randwick, Prince of Wales Hospital and Community Health Services, Randwick, NSW, Australia.
Melissa MiaoCentre for Health Systems and Safety Research, Australian Institute of Health Innovation, Macquarie University, North Ryde, NSW, Australia.
Johanna I WestbrookCentre for Health Systems and Safety Research, Australian Institute of Health Innovation, Macquarie University, North Ryde, NSW, Australia.
Andrew GeorgiouCentre for Health Systems and Safety Research, Australian Institute of Health Innovation, Macquarie University, North Ryde, NSW, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMolecular assays based on reverse transcription-polymerase chain reaction (RT-PCR) provide reliable results for the detection of respiratory pathogens, although diagnostic agreement varies. This study determined the agreement between the RT-PCR assays (Xpert

methodsWe retrospectively identified 914 patient encounters where testing with both Xpert

resultsThe positive percent agreement was 95.1% for influenza A, 87.5% for influenza B, and 77.8% for RSV. The negative percent agreement was 99.4% for influenza A, 99.9% for influenza B, and 100% for RSV. The prevalence and bias-adjusted kappa was 0.98 for influenza A, 0.99 for influenza B, and 0.97 for RSV. In a sensitivity analysis, the positive percent agreement values were significantly higher during the non-influenza season than the influenza season for influenza B and RSV.

conclusionsThe Xpert

Indexed as

Influenza, HumanRespiratory Syncytial Virus InfectionsHumansInfluenza A virusInfluenza B virusMolecular Diagnostic TechniquesNasopharynxRespiratory Syncytial VirusesRetrospective StudiesSensitivity and SpecificityAllplex™ RP1diagnostic agreementmolecular assaysXpert® Flu/RSV XC

Identifiers

PMID32815622
PMCPMC7461471

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.