Evidence map›Paper›PMID 32815621›Full record

ArticleObesity (Silver Spring, Md.)2020

Obesity Doubles Mortality in Patients Hospitalized for Severe Acute Respiratory Syndrome Coronavirus 2 in Paris Hospitals, France: A Cohort Study on 5,795 Patients.

Sébastien Czernichow, Nathanael Beeker, Claire Rives-Lange, Emmanuel Guerot, Jean-Luc Diehl, Sandrine Katsahian, Jean-Sébastien Hulot, Tigran Poghosyan, Claire Carette, Anne-Sophie Jannot and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Obesity (Silver Spring, Md.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 12 pooled it
2.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 12 syntheses or guidelines pooled it, 96 citations in OpenAlex.

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  2. Obesity as an independent risk factor for COVID-19 severity and mortality.The Cochrane database of systematic reviews · 2023
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Sébastien CzernichowUniversité de Paris, Paris, France.
Nathanael BeekerUniversité de Paris, Paris, France.
Claire Rives-LangeUniversité de Paris, Paris, France.
Emmanuel GuerotUniversité de Paris, Paris, France.
Jean-Luc DiehlUniversité de Paris, Paris, France.
Sandrine KatsahianUniversité de Paris, Paris, France.
Jean-Sébastien HulotUniversité de Paris, Paris, France.
Tigran PoghosyanUniversité de Paris, Paris, France.
Claire CaretteUniversité de Paris, Paris, France.
Anne-Sophie JannotUniversité de Paris, Paris, France.ORCID https://orcid.org/0000-0002-8001-8539
AP-HP / Universities / INSERM COVID-19 research collaboration and AP-HP COVID CDR Initiative
Université Paris Cité · FRInserm · FR

Funding

Assistance Publique - Hôpitaux de Paris
6 · The paper itself

Abstract

objectivePreliminary data from different cohorts of small sample size or with short follow-up indicate poorer prognosis in people with obesity compared with other patients. This study aims to precisely describe the strength of association between obesity in patients hospitalized with coronavirus disease 2019 (COVID-19) and mortality and to clarify the risk according to usual cardiometabolic risk factors in a large cohort.

methodsThis is a prospective cohort study including 5,795 patients aged 18 to 79 years hospitalized from February 1 to April 30, 2020, in the Paris area, with confirmed infection by severe acute respiratory syndrome coronavirus 2. Adjusted regression models were used to estimate the odds ratios (ORs) and 95% CIs for the mortality rate at 30 days across BMI classes, without and with imputation for missing BMI values.

resultsEight hundred ninety-one deaths had occurred at 30 days. Mortality was significantly raised in people with obesity, with the following ORs for BMI of 30 to 35 kg/m

conclusionsObesity doubles mortality in patients hospitalized with COVID-19.

Indexed as

Hospital MortalitySARS-CoV-2AdolescentAdultAgedBody Mass IndexCohort StudiesCOVID-19FemaleFranceHumansMaleMiddle AgedObesityOdds RatioParis

Identifiers

PMID32815621
PMCPMC7461006
OpenAlexW3049864503

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.