Evidence map›Paper›PMID 32815604›Full record

ArticleJournal of the American Geriatrics Society2020

Online Clinical Consensus Diagnosis of Dementia: Development and Validation.

Jinkook Lee, Mary Ganguli, Albert Weerman, Sandy Chien, Dong Young Lee, Mathew Varghese, Aparajit B Dey

Abstract readValidation StudyConsensus Statement
In one paragraph

Article in Journal of the American Geriatrics Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Superficial white matter and gray matter jointly support cognition among older adults in India.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  3. Article
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  10. Dementia caregiving in India: New evidence from a National representative sample.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  11. Article
  12. Article
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  14. Article
  15. Article
  16. Article
  17. Mental Health Impacts of COVID-19: Does Prepandemic Cognition and Dementia Status Matter?The journals of gerontology. Series A, Biological sciences and medical sciences · 2024
    Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Jinkook LeeCenter for Economic and Social Research, University of Southern California, Los Angeles, California, USA.
Mary GanguliDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0003-2762-7105
Albert WeermanCenter for Economic and Social Research, University of Southern California, Los Angeles, California, USA.
Sandy ChienCenter for Economic and Social Research, University of Southern California, Los Angeles, California, USA.
Dong Young LeeDepartment of Psychiatry, Seoul National University, Seoul, South Korea.
Mathew VargheseDepartment of Psychiatry, National Institute of Mental Health and Neuroscience, Bengaluru, India.
Aparajit B DeyDepartment of Geriatric Medicine, All India Institute of Medical Sciences, New Delhi, India.

Funding

Leveraging a natural experiment to estimate the causal impact of blood sugar on dementia and cognition in IndiaR01AG051125 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Jinkook Lee · 2015 to 2026
$26.8M
Modifiable Protective and Risk Factors of Late-Life Cognitive Health and DementiaRF1AG055273 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI LANGA, KENNETH M, LEE, JINKOOK · 2017 to 2017
$4.0M
Harmonizing Dementia Assessment in Korea: Study on Dynamics of the KLoSA MCI, Dementia & Labor LossR56AG056117 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI LEE, JINKOOK · 2018 to 2018
$698k
NIA NIH HHS R01 AG051125NIA NIH HHS R56 AG056117NIA NIH HHS RF1 AG055273
6 · The paper itself

Abstract

objectivesTo introduce cost-effective expert clinical diagnoses of dementia into population-based research using an online platform and to demonstrate their validity against in-person clinical assessment and diagnosis.

designThe online platform provides standardized data necessary for clinicians to rate participants on the Clinical Dementia Rating (CDR

settingAll India Institute of Medical Sciences (AIIMS), Delhi, and National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, India.

participantsThirty patients each at AIIMS and NIMHANS with equal numbers of patients previously independently rated in person by experts as CDR is 0 (cognitively normal), CDR is 0.5 (mild cognitive impairment), and CDR is 1 or greater (dementia). MEASUREMENTS: Multiple clinicians independently rate each participant on each CDR domain using standardized data and expert clinical judgment. The overall summary CDR is calculated by algorithm. When there are discrepancies among clinician ratings, clinicians discuss the case through a virtual consensus conference and arrive at a consensus overall rating.

resultsOnline clinical consensus diagnosis based on standardized interview data provides consistent clinical diagnosis with in-person clinical assessment and consensus diagnosis (κ coefficient = 0.76).

conclusionA web-based clinical consensus platform built on the Harmonized Diagnostic Assessment of Dementia for the Longitudinal Aging Study in India interview data is a cost-effective way to obtain reliable expert clinical judgments. A similar approach can be used for other epidemiological studies of dementia. J Am Geriatr Soc 68:S54-S59, 2020.

Indexed as

Cost-Benefit AnalysisDiagnosis, Computer-AssistedInternetAgedAlgorithmsDementiaFemaleHumansMaleMental Status and Dementia TestsMiddle AgedReproducibility of ResultsClinical Dementia Ratingclinical judgmentHarmonized Cognitive Assessment ProtocolLongitudinal Aging Study in Indiapopulation-based research

Identifiers

PMID32815604
PMCPMC7513553

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.