Evidence map›Paper›PMID 32815508›Full record

ArticleThe American journal of tropical medicine and hygiene2020

Liver Function Test Abnormalities in Experimental and Clinical

Anand Odedra, Lachlan Webb, Louise Marquart, Laurence J Britton, Stephan Chalon, Joerg J Moehrle, Nicholas M Anstey, Timothy William, Matthew J Grigg, David G Lalloo and 2 more

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Longitudinal changes in iron homeostasis in human experimental and clinical malaria.medRxiv : the preprint server for health sciences · 2023
    Article
  3. Article
  4. Article
  5. Epidemiological characteristics ofFrontiers in cellular and infection microbiology · 2022
    Article
  6. Article
  7. Article
  8. Molecular medicine reports · 2021
    Article
  9. Article
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 4 countries.

Anand OdedraQIMR Berghofer Medical Research Institute, Brisbane, Australia.
Lachlan WebbQIMR Berghofer Medical Research Institute, Brisbane, Australia.
Louise MarquartQIMR Berghofer Medical Research Institute, Brisbane, Australia.
Laurence J BrittonSchool of Medicine, The University of Queensland, Brisbane, Australia.
Stephan ChalonMedicines for Malaria Venture, Geneva, Switzerland.
Joerg J MoehrleMedicines for Malaria Venture, Geneva, Switzerland.
Nicholas M AnsteyGlobal and Tropical Health Division, Menzies School of Health Research, Darwin, Australia.
Timothy WilliamGleneagles Hospital, Kota Kinabalu, Malaysia.
Matthew J GriggGlobal and Tropical Health Division, Menzies School of Health Research, Darwin, Australia.
David G LallooLiverpool School of Tropical Medicine, Liverpool, United Kingdom.
Bridget E BarberGlobal and Tropical Health Division, Menzies School of Health Research, Darwin, Australia.
James S McCarthyQIMR Berghofer Medical Research Institute, Brisbane, Australia.
QIMR Berghofer Medical Research Institute · AUMenzies School of Health Research · AUMedicines for Malaria Venture · CHLiverpool School of Tropical Medicine · GBSabah Environmental Trust · MYThe University of Queensland · AU

Funding

Comparative incidence and clinical spectrum of Plasmodium knowlesi malaria, a longitudinal study in Sabah, MalaysiaR01AI116472 · NIAID · INFECTIOUS DISEASE SOCIETY KOTA KINABALU · PI WILLIAM, TIMOTHY · 2015 to 2019
$682k
NIAID NIH HHS R01 AI116472
6 · The paper itself

Abstract

Liver transaminase elevations after treatment in malaria volunteer infection studies (VISs) have raised safety concerns. We investigated transaminase elevations from two human

Indexed as

AdamantaneAdultAlanine TransaminaseAntimalarialsArtemisininsChloroquineCohort StudiesFemaleHumansLiver DiseasesLiver Function TestsMalaria, VivaxMalaysiaMaleParasitemiaPeroxidesAdamantaneAlanine TransaminaseAntimalarialsartefenomelartemisininArtemisininsChloroquinePeroxides

Identifiers

PMID32815508
PMCPMC7646782
OpenAlexW3050701901

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.