Evidence map›Paper›PMID 32815096›Full record

SynthesisBreast cancer (Tokyo, Japan)2021

Resistance training in breast cancer patients undergoing primary treatment: a systematic review and meta-regression of exercise dosage.

Pedro Lopez, Daniel A Galvão, Dennis R Taaffe, Robert U Newton, Giovani Souza, Gabriel S Trajano, Ronei S Pinto

Registry-linked trialAbstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Breast cancer (Tokyo, Japan), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06429189 (An Online Home-based Combined Exercise Intervention With Self-selected Intensity for Women With Breast Cancer), which is not on this map. Cited by 24 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06429189 naunknown statusnot on this mapstarted 2024, after this paper: background citation

An Online Home-based Combined Exercise Intervention With Self-selected Intensity for Women With Breast Cancer: The Home-Combo Randomized Controlled Trial.

TypeinterventionalSponsorGrupo LusófonaRan2024 to 2025Enrolled98ConditionsBreast Cancer, Chemotherapy EffectArmsHome-based combined exercise program with self-selected intensity
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Effects of resistance training on breast cancer-related arm lymphedema: a systematic review and dose-response meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Effect of exercise on body composition among women with ovarian cancer.Journal of cancer survivorship : research and practice · 2023
    Trial
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Resistance exercise dose effects on muscle morphology, muscle function and quality of life in advanced-stage ovarian cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Pedro LopezExercise Medicine Research Institute, Edith Cowan University, 270 Joondalup Drive, Perth, Western Australia, 6027, Australia. p.lopezda@our.ecu.edu.au.ORCID http://orcid.org/0000-0002-3897-667X
Daniel A GalvãoExercise Medicine Research Institute, Edith Cowan University, 270 Joondalup Drive, Perth, Western Australia, 6027, Australia.
Dennis R TaaffeExercise Medicine Research Institute, Edith Cowan University, 270 Joondalup Drive, Perth, Western Australia, 6027, Australia.
Robert U NewtonExercise Medicine Research Institute, Edith Cowan University, 270 Joondalup Drive, Perth, Western Australia, 6027, Australia.
Giovani SouzaExercise Research Laboratory, Physical Education, Physiotherapy, and Dance School, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.
Gabriel S TrajanoSchool of Exercise and Nutrition Sciences, Faculty of Health, Queensland University of Technology, Brisbane, Queensland, Australia.
Ronei S PintoExercise Research Laboratory, Physical Education, Physiotherapy, and Dance School, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExercise is recognised as an adjunct therapy for breast cancer patients; however, little is known about the resistance training dose-response. We conducted a systematic review and meta-regression to examine the resistance training dose-response (i.e., volume and intensity) in breast cancer patients undergoing primary treatment.

methodsSearches in MEDLINE, CINAHL, and SPORTDiscus were conducted for studies published up to November 2019. Experimental studies that evaluated resistance-based exercise interventions in women with breast cancer undergoing primary treatment were included. Information about resistance training components, average change and change per week, as well as standardised mean difference were extracted, and used for meta-regression analysis. Outcome measures were upper and lower body muscle strength and body composition.

results10 trials were included in the systematic review and 4 trials in the dose-response analysis. Resistance training weekly prescribed volume was inversely associated with increases in upper and lower body muscle strength (r

conclusionLow volume resistance training might be a suitable exercise recommendation for breast cancer patients undergoing primary treatment producing superior benefits for muscle strength compared to higher volume training, regardless of the training intensity. Low volume resistance training may provide a conservative and appropriate approach for breast cancer patients, allowing gradual progression and modification throughout the exercise program.

Indexed as

ChemoradiotherapyBody CompositionBreast NeoplasmsFemaleHumansMuscle StrengthRegression AnalysisResistance TrainingTreatment OutcomeBreast cancerDose–response effectsHealth-related outcomesResistance training

Identifiers

PMID32815096

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.