Evidence map›Paper›PMID 32814986›Full record

Observational studyRheumatology international2020

Clinical performance of ASAS Health Index in patients with ankylosing spondylitis and non-radiographic axial spondyloarthritis: real-world evidence from Multicenter Nationwide Registry.

Ozgur Akgul, Hatice Bodur, Sebnem Ataman, Fatma Gul Yurdakul, Erhan Capkin, Gulcan Gurer, Ilhan Sezer, Mehmet Tuncay Duruoz, Meltem Alkan Melikoglu, Hasan Fatih Cay and 5 more

Abstract readMulticenter StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in Rheumatology international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  6. Review
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  12. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Ozgur AkgulDepartment of Physical Medicine and Rehabilitation, Division of Rheumatology, Manisa Celal Bayar University School of Medicine, Manisa, Turkey. ozgur.akgul@cbu.edu.tr.ORCID http://orcid.org/0000-0003-3012-2968
Hatice BodurDepartment of Physical Medicine and Rehabilitation, Ankara City Hospital, Universiteler Mah. 1604. Cad. Cankaya, Ankara, Turkey.ORCID http://orcid.org/0000-0003-3008-7007
Sebnem AtamanDepartment of Physical Medicine and Rehabilitaton, Division of Rheumatology, Faculty of Medicine, Ankara University, Ankara, Turkey.ORCID http://orcid.org/0000-0003-3570-3825
Fatma Gul YurdakulDepartment of Physical Medicine and Rehabilitation, Ankara City Hospital, Universiteler Mah. 1604. Cad. Cankaya, Ankara, Turkey.ORCID http://orcid.org/0000-0001-8630-9233
Erhan CapkinDepartment of Physical Medicine and Rehabilitation, Karadeniz Technical University School of Medicine, Trabzon, Turkey.ORCID http://orcid.org/0000-0003-2728-5934
Gulcan GurerDepartment of Physical Medicine and Rehabilitation, Division of Rheumatology, Adnan Menderes University School of Medicine, Aydin, Turkey.ORCID http://orcid.org/0000-0001-8287-2264
Ilhan SezerDepartment of Physical Medicine and Rehabilitation, Division of Rheumatology, Akdeniz University School of Medicine, Antalya, Turkey.ORCID http://orcid.org/0000-0003-1324-2108
Mehmet Tuncay DuruozDepartment of Physical Medicine and Rehabilitation, Division of Rheumatology, Marmara University School of Medicine, Istanbul, Turkey.ORCID http://orcid.org/0000-0003-3584-2788
Meltem Alkan MelikogluDepartment of Physical Medicine and Rehabilitation, Division of Rheumatology, Ataturk University School of Medicine, Erzurum, Turkey.ORCID http://orcid.org/0000-0001-7519-9470
Hasan Fatih CayDepartment of Rheumatology, Saglik Bilimleri University, Antalya Education and Research Hospital, Antalya, Turkey.ORCID http://orcid.org/0000-0001-5466-7482
Aylin RezvaniDepartment of Physical Medicine and Rehabilitation, Medipol University School of Medicine, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-5852-3854
Ilker YagciDepartment of Physical Medicine and Rehabilitation, Marmara University School of Medicine, İstanbul, Turkey.ORCID http://orcid.org/0000-0002-5988-7369
Feride GogusDepartment of Physical Medicine and Rehabilitation, Division of Rheumatology, Gazi University School of Medicine, Ankara, Turkey.ORCID http://orcid.org/0000-0003-0921-5991
Ayhan KamanliDepartment of Physical Medicine and Rehabilitation, Division of Rheumatology, Sakarya University School of Medicine, Sakarya, Turkey.ORCID http://orcid.org/0000-0001-5299-7250
Remzi CevikDepartment of Physical Medicine and Rehabilitation, Dicle University School of Medicine, Diyarbakir, Turkey.ORCID http://orcid.org/0000-0002-4124-1586

Funding

Turkish League Against Rheumatism 06.23.2018-16
6 · The paper itself

Abstract

The Assessment of SpondyloArthritis international Society Health Index (ASAS HI) is used as a new instrument in measuring the function, disability and health of patients with spondyloarthritis (SpA). However, the real-world evidence of ASAS HI is very limited. In the present study, our objective is to evaluate the psychometric properties and performance of ASAS HI in the real-world setting as well as comparing ASAS HI with the current instruments to assess the construct validity and determine the cut-off points in patients with both ankylosing spondylitis (AS) and non-radiographic axial spondyloarthritis (nr-axSpA). A total of 991 patients with axSpA who fulfilled either the ASAS classification criteria for axial SpA (axSpA) or the Modified New York Criteria (mNY) for AS were recruited from the Biologic and targeted Synthetic antirheumatic drugs Registry (BioStaR) SpA. The construct validity of ASAS HI against the Bath Ankylosing Spondylitis Disease Activities Index (BASDAI) and Ankylosing Spondylitis Disease Activity Score-C-Reactive Protein (ASDAS-CRP) the Bath Ankylosing Spondylitis Functional index (BASFI) was performed. Using the receiver operating characteristic (ROC) curves analysis, the cut-off points were calculated. Of all the recruited patients, 851 (85.9%) were AS and 140 (14.1%) were nr-axSpA. The difference in the mean ASAS HI scores of the patients with AS and the ones with nr-axSpA were not statistically significant (6.12 ± 4.29 and 6.42 ± 4.86, respectively). The mean ASAS HI score was significantly higher in females and small city residents. The ASAS HI had a strong construct validity against ASDAS-CRP, BASDAI and BASFI. A cut-off point of ≤ 4 was determined to discriminate good and moderate, as well as ≥ 12 to discriminate moderate and poor health status. In conclusion, ASAS HI is a reliable instrument to evaluate health and functioning for both patients with AS and nr-axSpA in clinical practice.

Indexed as

Activities of Daily LivingQuality of LifeAdultFemaleHumansMaleMiddle AgedPsychometricsRegistriesReproducibility of ResultsSpondylarthropathiesSpondylitis, AnkylosingSurveys and QuestionnairesTurkeyAnkylosing spondylitisFunctional performanceHealth-related quality of lifeHealth Status Index

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.