Evidence map›Paper›PMID 32814882›Full record

ArticleNature2020

Reply to: APP gene copy number changes reflect exogenous contamination.

Ming-Hsiang Lee, Christine S Liu, Yunjiao Zhu, Gwendolyn E Kaeser, Richard Rivera, William J Romanow, Yasuyuki Kihara, Jerold Chun

Abstract readLetterComment
In one paragraph

Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Brain Somatic Mutation in Aging and Alzheimer's Disease.Annual review of genomics and human genetics · 2021
    Review
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Ming-Hsiang Lee *Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.ORCID http://orcid.org/0000-0003-3174-8372
Christine S Liu *Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-1239-4612
Yunjiao ZhuSanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.
Gwendolyn E KaeserSanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.
Richard RiveraSanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.
William J RomanowSanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.
Yasuyuki KiharaSanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.ORCID http://orcid.org/0000-0001-7462-3006
Jerold ChunSanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA. jchun@sbpdiscovery.org.ORCID http://orcid.org/0000-0003-3964-0921

Funding

VIRUS-INDUCED BRAIN PATHOLOGYP50AG005131 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BREWER, JAMES B · 1985 to 2018
$55.4M
UCSD Shiley-Marcos Alzheimer's Disease Research Center P30P30AG062429 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Steven Dyal Edland · 2019 to 2026
$34.9M
Transformative research on the normal and Alzheimer's disease brain through studies of neuronal gene recombinationR56AG067489 · NIA · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI CHUN, JEROLD · 2019 to 2019
$2.4M
S1P signaling machinery in neuroimmune interactionsR01NS103940 · NINDS · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI KIHARA, YASUYUKI · 2018 to 2022
$2.1M
NIA NIH HHS P30 AG062429NIA NIH HHS P50 AG005131NIA NIH HHS R56 AG067489NINDS NIH HHS R01 NS103940
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DNA Copy Number VariationsGene Dosage

Identifiers

PMID32814882
PMCPMC8522531

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.