Evidence map›Paper›PMID 32814470›Full record

ArticleThe Journal of international medical research2020

Antiplatelet therapy may be safe in ischemic stroke patients with cerebral microbleed.

Ningqin Meng, Wei Zhang, Ying Su, Ziming Ye, Chao Qin

Open access · goldAbstract read
In one paragraph

Article in The Journal of international medical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ningqin MengThe First Affiliated Hospital of Guangxi Medical University, Department of Neurology, Nanning, Guangxi, China.ORCID https://orcid.org/0000-0003-1966-9815
Wei ZhangJiangbin Hospital, Department of Neurology, Nanning, Guangxi, China.
Ying SuThe First Affiliated Hospital of Guangxi Medical University, Department of Neurology, Nanning, Guangxi, China.
Ziming YeThe First Affiliated Hospital of Guangxi Medical University, Department of Neurology, Nanning, Guangxi, China.
Chao QinThe First Affiliated Hospital of Guangxi Medical University, Department of Neurology, Nanning, Guangxi, China.ORCID https://orcid.org/0000-0002-0295-4655
Guangxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe examined whether antiplatelet therapy is safe for ischemic stroke patients with cerebral microbleed.

methodsWe retrospectively analyzed ischemic stroke patients admitted to our hospital from 2015 to 2018. Baseline information was extracted from the computerized database. Adverse events, including symptomatic cerebral hemorrhage, recurrent cerebral infarction, and death, were collected by phone.

resultsA total of 184 ischemic stroke patients were examined, including 106 with and 78 without cerebral microbleed. No patient experienced symptomatic cerebral hemorrhage after discharge. Patients with cerebral microbleed had a higher prevalence of hypertension (92% vs 74%) and suffered from more serious leukoaraiosis (3.0 ± 1.7 vs 1.3 ± 1.4 points on the Fazekas scale). Leukoaraiosis scores were correlated with the number of cerebral microbleeds (r = 0.42).

conclusionsAntiplatelet therapy may be safe for ischemic stroke patients with cerebral microbleed. The risk-benefit ratio should be carefully evaluated before withholding antiplatelet therapy.

Indexed as

Brain IschemiaIschemic StrokeStrokeCerebral HemorrhageHumansMagnetic Resonance ImagingPlatelet Aggregation InhibitorsRetrospective StudiesRisk FactorsPlatelet Aggregation Inhibitorsadverse eventantiplatelet therapyCerebral microbleedhemorrhageleukoaraiosisstroke

Identifiers

PMID32814470
PMCPMC7444122
OpenAlexW3080730981

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.