Evidence map›Paper›PMID 32814099›Full record

ReviewInternational journal of biological macromolecules2020

Silk fibroin and silk-based biomaterial derivatives for ideal wound dressings.

Priyanka P Patil, Michaela R Reagan, Raghvendra A Bohara

Open access · greenAbstract readComparative StudyReview
In one paragraph

Review in International journal of biological macromolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 189 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Priyanka P PatilSigma Institute of Science and Commerce, Bakrol, Vadodara, Gujarat 390019, India.
Michaela R ReaganMaine Medical Centre Research Institute, Scarborough, ME 04106, USA.
Raghvendra A BoharaCÚRAM, SFI Research Centre for Medical Devices, National University of Ireland Galway, Ireland; Centre for Interdisciplinary Research, D. Y. Patil Education Society (Institution Deemed to be University), Kolhapur 416006, India. Electronic address: raghvendrabohara@gmial.com.
Ollscoil na Gaillimhe – University of Galway · IE

Funding

Understanding Factors Influencing COVID-19 Testing and Vaccination in Immigrant Low-income and Homeless Populations and Testing Targeted InterventionsU54GM115516 · NIGMS · MAINEHEALTH · PI CLIFFORD JAMES ROSEN · 2017 to 2026
$51.6M
The role of night shift work in metabolic disorders during and after pregnancyP20GM121301 · NIGMS · MAINEHEALTH · PI CLIFFORD JAMES ROSEN · 2017 to 2026
$25.1M
Progenitor Cell Analysis CoreP30GM106391 · NIGMS · MAINEHEALTH · PI FRIESEL, ROBERT E · 2013 to 2017
$5.7M
NIGMS NIH HHS P20 GM121301NIGMS NIH HHS P30 GM106391NIGMS NIH HHS U54 GM115516
6 · The paper itself

Abstract

Silk fibroin (SF) is derived from Bombyx mori silkworm cocoons and has been used in textiles and as a suture material for decades. More recently, SF has been used for various new biomedical applications, including as a wound dressing, owing to its excellent biological and mechanical properties. Specifically, the mechanical stiffness, versatility, biocompatibility, biodegradability, water vapour permeability and slight bactericidal properties make SF an excellent candidate biomaterial for wound dressing applications. The effectiveness of SF as a wound dressing has been tested and well-documented in vitro as well as in-vivo, as described here. Dressings based on SF are currently used for treating a wide variety of chronic and acute (e.g. burn) wounds. SF and its derivatives prepared as biomaterials are available as sponges, hydrogels, nanofibrous matrices, scaffolds, micro/nanoparticles, and films. The present review discusses the potential role of SF in wound dressing and its modulation for wound dressing applications. The comparison of SF based dressings with other natural polymers understands the readers, the scope and limitation of the subject in-depth.

Indexed as

BandagesAnimalsBandages, HydrocolloidBiocompatible MaterialsBiopolymersChemical PhenomenaFibroinsHumansHydrogelsManufactured MaterialsMaterials TestingNanostructuresPolyvinyl AlcoholRatsRats, Sprague-DawleySilkBiocompatible MaterialsBiopolymersFibroinsHydrogelsPolyvinyl AlcoholSilkZinc OxideBiomaterialsFilmsHydrogelsMicro-nanoparticlesNanofibrous matricesScaffoldsSF proteinSpongesWound dressing

Identifiers

PMID32814099
PMCPMC7849047
OpenAlexW3049104930

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.