Evidence map›Paper›PMID 32813903›Full record

ArticleHuman brain mapping2020

Visual stimuli induce serotonin release in occipital cortex: A simultaneous positron emission tomography/magnetic resonance imaging study.

Hanne Demant Hansen, Ulrich Lindberg, Brice Ozenne, Patrick MacDonald Fisher, Annette Johansen, Claus Svarer, Sune Høgild Keller, Adam Espe Hansen, Gitte Moos Knudsen

Open access · goldAbstract read
In one paragraph

Article in Human brain mapping, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. ACS chemical neuroscience · 2024
    Article
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Hanne Demant HansenNeurobiology Research Unit and NeuroPharm, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.ORCID 0000-0001-5564-7627
Ulrich LindbergDepartment of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-0004-6354
Brice OzenneNeurobiology Research Unit and NeuroPharm, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Patrick MacDonald FisherNeurobiology Research Unit and NeuroPharm, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Annette JohansenNeurobiology Research Unit and NeuroPharm, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Claus SvarerNeurobiology Research Unit and NeuroPharm, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Sune Høgild KellerDepartment of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Adam Espe HansenDepartment of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Gitte Moos KnudsenNeurobiology Research Unit and NeuroPharm, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
University of Copenhagen · DKCopenhagen University Hospital · DK

Funding

H2020 Marie Skłodowska-Curie Actions 746850Innovationsfonden 4108-00004BLundbeckfonden R165-2013-15637Lundbeckfonden R231-2016-3236
6 · The paper itself

Abstract

Endogenous serotonin (5-HT) release can be measured noninvasively using positron emission tomography (PET) imaging in combination with certain serotonergic radiotracers. This allows us to investigate effects of pharmacological and nonpharmacological interventions on brain 5-HT levels in living humans. Here, we study the neural responses to a visual stimulus using simultaneous PET/MRI. In a cross-over design, 11 healthy individuals were PET/MRI scanned with the 5-HT

Indexed as

AdultAffectBenzopyransCerebrovascular CirculationCross-Over StudiesHumansMagnetic Resonance ImagingMemory, EpisodicMorpholinesMultimodal ImagingOccipital LobePiperazinesPositron-Emission TomographyReceptor, Serotonin, 5-HT1BSerotoninVisual Perception5-methyl-8-(4-methyl-piperazin-1-yl)-4-oxo-4H-chromene-2-carboxylic acid (4-morpholin-4-yl-phenyl)amideBenzopyransHTR1B protein, humanMorpholinesPiperazinesReceptor, Serotonin, 5-HT1BSerotonin[11C]AZ104193695-HT5-HT1B receptorsimultaneous PET/MRvisual stimulation

Identifiers

PMID32813903
PMCPMC7555083
OpenAlexW3052908524

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.