ArticleActa cirurgica brasileira2020
Topical application of lidocaine or bupivacaine in the healing of surgical wounds in dogs.
Article in Acta cirurgica brasileira, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 7 citations in OpenAlex.
- Use of polyhexamethylene biguanide on wound healing in dogs.Acta cirurgica brasileira · 2026Article
- A Novel Comprehensive Therapeutic Approach to the Challenges of Chronic Wounds: A Brief Review and Clinical Experience Report.Advances in therapy · 2024Review
- Systematic literature review of topical local anaesthesia or analgesia to donor site wounds.Burns & trauma · 2022Article
- The Wound Reporting in Animal and Human Preclinical Studies (WRAHPS) Guidelines.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair SocietyArticle
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo analyze the anesthetic drugs interference with wound healing when used in the surgical bed.
methodsMacro and microscopic aspects of healing of surgical wounds were evaluated after instillation of topical anesthetics without vasoconstrictor or saline solution 0.9% as control in the transsurgical period. Thirty dogs, males and females were divided into two experimental groups. In both groups, two circular punch lesions of 6 mm diameter were performed in the abdomen. In group 1, lidocaine was instilled in one of the lesions and saline solution in the contralateral lesion. In group 2 the procedure was repeated with the use of bupivacaine. The macroscopic assessment of the lesions was performed on the first, third and tenth postoperative day. The excisional biopsy was performed on the tenth day and the samples were submitted for histopathological examination.
resultsThe macroscopic analysis had a significant difference between groups. Microscopic analysis was not significant between groups.
conclusionsThe topical application of lidocaine and bupivacaine in the surgical wound is feasible and it does not influence skin healing. The benefit of such a practice, which has been the subject of other studies, seems to outweigh the risks.
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Registered trials
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