SynthesisAlimentary pharmacology & therapeutics2020
Systematic review with meta-analysis: efficacy of balloon-assisted enteroscopy for dilation of small bowel Crohn's disease strictures.
Synthesis in Alimentary pharmacology & therapeutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it, 82 citations in OpenAlex.
- Efficacy and Safety of Endoscopic Stricturotomy in Inflammatory Bowel Disease-Related Strictures: A Systematic Review and Meta-Analysis.Digestive diseases and sciences · 2024Pooled it
- Therapeutic Balloon-Assisted Enteroscopy: Recent Advances in the Management of Small Bowel Diseases.DEN open · 2027Review
- Endoscopic stricture management in inflammatory bowel disease: Present and future.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026Review
- Endoscopic Treatment for Crohn's Disease-Related Deep Small Intestinal Strictures: Balloon-Assisted Enteroscopy-Guided Stricturotomy Versus Balloon Dilation Therapy-A Single-Center Retrospective Study.Digestive diseases and sciences · 2026Article
- Efficacy and Safety of Endoscopic Strictureplasty and Stricturotomy for Crohn's Disease-Associated Strictures: A Systematic Review and Current Perspective.Diseases (Basel, Switzerland) · 2026Review
- Recent Endoscopic Technological Advancements in Crohn's Stricture Dilation.Current gastroenterology reports · 2026Review
- Phenotype-driven management in ileocecal Crohn's disease: a narrative review with a proposed research framework.Therapeutic advances in gastroenterology · 2026Review
- The role of enteroscopy in the diagnosis and interventional management of small intestine diseases.Therapeutic advances in gastroenterology · 2026Review
- Automated assessment of small bowel and colon cleansing in enteroscopy using a convolutional neural network.Endoscopy international open · 2026Article
- Endoscopic Management of Complicated Small Bowel Crohn's Disease.Current gastroenterology reports · 2025Review
- Article
- Enteroscopic Balloon Dilation in Small Bowel Stricturing Crohn's Disease: Long-Term Outcomes and Risk Factors for Surgery in a Single-Center Prospective Observational Study.United European gastroenterology journal · 2025Observational
- Preliminary study on the clinical value of endoscopic stricturotomy in the treatment of stricturing Crohn's disease.World journal of gastrointestinal surgery · 2025Article
- Effectiveness of biologics for endoscopic healing in patients with isolated proximal small bowel Crohn's disease.World journal of gastroenterology · 2025Article
- Discrimination between Inflammatory and Fibrotic Activity in Crohn's Disease-Associated Ileal-Colonic Anastomotic Strictures by Combined Ga-68-FAPI-46 and F-18-FDG-PET/CT Imaging.Visceral medicine · 2025Article
- Endoscopic Management of Strictures in Crohn's Disease: An Unsolved Case.Journal of clinical medicine · 2024Review
- A global consensus on the definitions, diagnosis and management of fibrostenosing small bowel Crohn's disease in clinical practice.Nature reviews. Gastroenterology & hepatology · 2024Article
- Endoscopic Characteristics of Small-Bowel Gastrointestinal Stromal Tumors Detected During Single-Balloon Enteroscopy: A Retrospective Analysis.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2024Article
- Interventional endoscopy in inflammatory bowel disease: a comprehensive review.Gastroenterology report · 2024Review
- Stricture dilationTherapeutic advances in gastroenterology · 2024Article
Corrections and comments
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Authors and funding
17 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundEvidence for endoscopic balloon dilation of small intestinal strictures in Crohn's disease (CD) using balloon-assisted enteroscopy is scarce.
aimTo evaluate endoscopic balloon dilation for the treatment of small intestinal CD strictures using balloon-assisted enteroscopy.
methodsCitations in Embase, MEDLINE, and Cochrane were systematically reviewed. In a meta-analysis of 18 studies with 463 patients and 1189 endoscopic balloon dilations, technical success was defined as the ability to dilate a stricture. Individual data were also obtained on 218 patients to identify outcome-relevant risk factors.
resultsIn the pooled per-study analysis, technical success rate of endoscopic balloon dilation was 94.9%, resulting in short-term clinical efficacy in 82.3% of patients. Major complications occurred in 5.3% of patients. During follow-up, 48.3% of patients reported symptom recurrence, 38.8% were re-dilated and 27.4% proceeded to surgery. On the per-patient-based multivariable analysis, that patients with disease activity in the small intestine had lower short-term clinical efficacy (odds ratio 0.32; 95% confidence interval 0.14-0.73, P = 0.007). Patients with concomitant active disease in the small and/or large intestine had an increased risk to proceed toward surgery (hazard ratio 1.85; 95% confidence interval 1.09-3.13, P = 0.02 and hazard ratio 1.77; 95% confidence interval 1.34-2.34, P < 0.001).
conclusionsBalloon-assisted enteroscopy for dilatation of CD-associated small intestinal strictures has high short-term technical and clinical efficacy and low complication rates. However, up to two-thirds of patients need re-dilation or surgery.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.