Evidence map›Paper›PMID 32813261›Full record

ReviewCurrent heart failure reports2020

Epitranscriptomics in the Heart: a Focus on m

Jacob Z Longenecker, Christopher J Gilbert, Volha A Golubeva, Colton R Martens, Federica Accornero

Open access · greenAbstract readReview
In one paragraph

Review in Current heart failure reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Epitranscriptomic Regulations in the Heart.Physiological research · 2024
    Review
  6. Article
  7. Article
  8. RNA modification mEpigenetics · 2023
    Review
  9. Frontiers in cardiovascular medicine · 2023
    Article
  10. The role of mFrontiers in endocrinology · 2023
    Review
  11. Review
  12. Review
  13. Review
  14. Epitranscriptomics of cardiovascular diseases (Review).International journal of molecular medicine · 2022
    Review
  15. Article
  16. NCell death discovery · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jacob Z LongeneckerDepartment of Physiology and Cell Biology, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University, 473 W 12th Ave, Columbus, OH, 43210, USA.
Christopher J GilbertDepartment of Physiology and Cell Biology, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University, 473 W 12th Ave, Columbus, OH, 43210, USA.
Volha A GolubevaDepartment of Physiology and Cell Biology, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University, 473 W 12th Ave, Columbus, OH, 43210, USA.
Colton R MartensDepartment of Physiology and Cell Biology, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University, 473 W 12th Ave, Columbus, OH, 43210, USA.
Federica AccorneroDepartment of Physiology and Cell Biology, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University, 473 W 12th Ave, Columbus, OH, 43210, USA. federica.accornero@osumc.edu.
The Ohio State University · US

Funding

Post-transcriptional regulation of cardiac hypertrophyR01HL136951 · NHLBI · OHIO STATE UNIVERSITY · PI Federica Accornero · 2017 to 2026
$4.7M
NHLBI NIH HHS R01 HL136951
6 · The paper itself

Abstract

purpose of reviewPost-transcriptional modifications are key regulators of gene expression that allow the cell to respond to environmental stimuli. The most abundant internal mRNA modification is N6-methyladenosine (m RECENT

findingsStudies have primarily relied on gain and loss of function models for the enzymes responsible for adding and removing the m

Indexed as

Epigenesis, GeneticAdenosineGenome-Wide Association StudyHeart FailureHumansRNA, MessengerSignal TransductionAdenosineN-methyladenosineRNA, MessengerEpigeneticsHeart failurem6ARNA methylation

Identifiers

PMID32813261
PMCPMC7486268
OpenAlexW3076285380

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.