Evidence map›Paper›PMID 32813126›Full record

ArticleArchives of orthopaedic and trauma surgery2022

Modelling gluteus medius tendon degeneration and repair in a large animal model.

Mark Zhu, David Musson, Mark Oliver, Elwyn Firth, Jillian Cornish, Jacob Munro

Abstract read
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In one paragraph

Article in Archives of orthopaedic and trauma surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. A novel augmentation technique for the repair of full thickness gluteal tendon tears: a biomechanical analysis in an ovine model.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2025
    Article
  3. Animal model for tendinopathy.Journal of orthopaedic translation · 2023
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mark ZhuBone and Joint Laboratory, University of Auckland, 85 Park Road, Grafton, 1023, New Zealand. mzhu031@aucklanduni.ac.nz.ORCID http://orcid.org/0000-0002-9856-4618
David MussonBone and Joint Laboratory, University of Auckland, 85 Park Road, Grafton, 1023, New Zealand.
Mark OliverLiggins Institute, University of Auckland, 85 Park Road, Grafton, New Zealand.
Elwyn FirthLiggins Institute, University of Auckland, 85 Park Road, Grafton, New Zealand.
Jillian CornishBone and Joint Laboratory, University of Auckland, 85 Park Road, Grafton, 1023, New Zealand.
Jacob MunroBone and Joint Laboratory, University of Auckland, 85 Park Road, Grafton, 1023, New Zealand.

Funding

Health Research Council of New Zealand 3714609New Zealand Orthopaedic Association 371455
6 · The paper itself

Abstract

introductionGluteus medius tendon tears often occur in the context of chronic tendinopathy and remain a difficult clinical problem. Surgical repair is challenging as it is often delayed and performed in degenerative tendons. No animal model currently exists to mimic the delayed repair of tendinopathic gluteus medius tears. The aims of this study were to develop a chronic model of gluteus medius tendinopathy and tear and then compare this model to an acute gluteus medius tear and repair. MATERIALS AND

methodsSix gluteus medius muscles were dissected and examined in mature sheep to confirm anatomical similarity to the human counterpart. Ten separate adult sheep underwent tendon detachment, followed by relook and histological sampling at 6 and 16 weeks to assess the extent of tendon degeneration. Six adult sheep underwent tendon repair at 6 weeks and were later assessed for healing of the tendon and compared to a further four adult sheep who underwent an acute tendon detachment and repair procedure.

resultsThe sheep gluteus medius muscle consisted of three compartments, the anterior, middle and posterior. All compartments inserted via the common tendon on the superolateral aspect of the greater trochanter. At both 6 and 16 weeks, there was significant tendinopathic changes on histology compared to controls as assessed by modified Movin's score (p = 0.018, p = 0.047) but no difference between the 6- and 16-week groups (p = 0.25). There were significant differences between delayed and acute repair in both histological appearance (p = 0.025) and biomechanical properties (p = 0.019), with acute repair superior in both.

conclusionsTendon detachment for 6 weeks is sufficient to produce histological changes similar to chronic tendinopathy and repair of this degenerative tendon results in significantly poorer healing when compared to an acute repair model. Animal models for gluteus medius tears should use a delayed repair model to improve clinical validity.

Indexed as

TendinopathyTendonsAnimalsButtocksDisease Models, AnimalMuscle, SkeletalSheepAnimal modelHip jointHistologyMuscleSheepTendons

Identifiers

PMID32813126

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.