ArticleNeuroradiology2021
Qualitative versus automatic evaluation of CT perfusion parameters in acute posterior circulation ischaemic stroke.
Article in Neuroradiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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12 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Software with artificial intelligence-derived algorithms for analysing CT brain scans in people with a suspected acute stroke: a systematic review and cost-effectiveness analysis.Health technology assessment (Winchester, England) · 2024Pooled it
- Endovascular Revascularization for Chronic Vertebral Artery Occlusion with Poor Collateral Circulation and a Large Perfusion Abnormality Identified by Automated Perfusion Imaging: A Case Report.Journal of neuroendovascular therapy · 2026Article
- Assessment of Perfusion Volumes by a New Automated Software for Computed Tomography Perfusion.Stroke and vascular neurology · 2024Article
- Enhancing Stroke Recognition: A Comparative Analysis of Balance and Eyes-Face, Arms, Speech, Time (BE-FAST) and Face, Arms, Speech, Time (FAST) in Identifying Posterior Circulation Strokes.Journal of clinical medicine · 2024Article
- Diagnostic accuracy of large and medium vessel occlusions in acute stroke imaging by neurology residents and stroke fellows: A comparison of CT angiography alone and CT angiography with CT perfusion.European stroke journal · 2024Article
- A retrospective study of non-equidistant interstitial brain CT perfusion scanning and prediction of time to peak.Heliyon · 2024Article
- Imaging Factors Associated With Poor Outcome in Patients With Basilar Artery Occlusion Treated With Endovascular Thrombectomy.Stroke (Hoboken, N.J.) · 2023Article
- The value of computed tomography perfusion deficit volumes in acute isolated brainstem infarction.Frontiers in neurology · 2023Article
- Optimal CT perfusion thresholds for core and penumbra in acute posterior circulation infarction.Frontiers in neurology · 2023Article
- Mechanical thrombectomy for acute posterior cerebral artery stroke; Feasibility and predictors of outcome.Neuroradiology · 2022Article
- Predictive value of Tmax perfusion maps on final core in acute ischemic stroke: an observational single-center study.La Radiologia medica · 2022Observational
- Editorial: Challenges in Posterior Circulation Ischemic Stroke.Frontiers in neurology · 2021Article
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo compare the diagnostic accuracy (ACC) in the detection of acute posterior circulation strokes between qualitative evaluation of software-generated colour maps and automatic assessment of CT perfusion (CTP) parameters.
methodsWere retrospectively collected 50 patients suspected of acute posterior circulation stroke who underwent to CTP (GE "Lightspeed", 64 slices) within 24 h after symptom onset between January 2016 and December 2018. The Posterior circulation-Acute Stroke Prognosis Early CT Score (pc-ASPECTS) was used for quantifying the extent of ischaemic areas on non-contrast (NC)CT and colour-coded maps generated by CTP4 (GE) and RAPID (iSchemia View) software. Final pc-ASPECTS was calculated on follow-up NCCT and/or MRI (Philips Intera 3.0 T or Philips Achieva Ingenia 1.5 T). RAPID software also elaborated automatic quantitative mismatch maps.
resultsBy qualitative evaluation of colour-coded maps, MTT-CTP4D and Tmax-RAPID showed the highest sensitivity (SE) (88.6% and 90.9%, respectively) and ACC (84% and 88%, respectively) compared with the other perfusion parameters (CBV, CBF). Baseline NCCT and CBF provided by RAPID quantitative perfusion mismatch maps had the lowest SE (29.6% and 6.8%, respectively) and ACC (38% and 18%, respectively). CBF and Tmax assessment provided by quantitative RAPID perfusion mismatch maps showed significant lower SE and ACC than qualitative evaluation. No significant differences were found between the pc-ASPECTSs assessed on colour-coded MTT and Tmax maps neither between the scores assessed on colour-coded CBV-CTP4D and CBF-RAPID maps.
conclusionQualitative analysis of colour-coded maps resulted more sensitive and accurate in the detection of ischaemic changes than automatic quantitative analysis.
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