ArticleMetabolism open2020
Functional modulation of gut microbiota in diabetic rats following dietary intervention with pistachio nuts (
Article in Metabolism open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 44 citations in OpenAlex.
- Article
- Physicochemical, microbial, and microbiome dynamics in winery waste composting.Environmental science and pollution research international · 2025Article
- Assessment of ImmobilizedFoods (Basel, Switzerland) · 2024Article
- Functional Modulation of Gut Microbiota and Blood Parameters in Diabetic Rats Following Dietary Intervention with Free or ImmobilizedNutrients · 2024Article
- Evaluating Inclusion of Commercial Pistachio By-Product as a Functional Ingredient in Rainbow Trout Fishmeal and Plant Meal-Based Diets.Antioxidants (Basel, Switzerland) · 2024Article
- Effects of Free or ImmobilizedMicroorganisms · 2024Article
- Diet patterns, gut microbiota and metabolic disorders: Perspectives and challenges.Metabolism open · 2024Article
- Novel Wild-TypeMicroorganisms · 2024Article
- Effects of Peanuts and Pistachios on Gut Microbiota and Metabolic Syndrome: A Review.Foods (Basel, Switzerland) · 2023Review
- Believe It or 'Nutrients · 2023Review
- Article
- Article
- Exploration of the mechanisms underlying the beneficial effect of Luo Tong formula on retinal function in diabetic rats via the "gut microbiota-inflammation-retina" axis.Chinese medicine · 2022Article
- Why Should Pistachio Be a Regular Food in Our Diet?Nutrients · 2022Review
- Pistachio Nuts (Plants (Basel, Switzerland) · 2021Review
- Maintaining Digestive Health in Diabetes: The Role of the Gut Microbiome and the Challenge of Functional Foods.Microorganisms · 2021Review
- The Nutritional Potential of the Native Australian Green Plum (Frontiers in nutrition · 2020Review
- The Alteration in Composition and Function of Gut Microbiome in Patients with Type 2 Diabetes.Journal of diabetes research · 2020Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGut microbiota holds a key-role in numerous biological functions and has emerged as a driving force for the development of diabetes. Diet contributes to gut microbiota diversity and functionality providing a tool for the prevention and management of the disease. The study aimed to investigate the effect of a dietary intervention with pistachio nuts, a rich source of monounsaturated fatty acids, dietary fibers and phytochemicals on gut microbiota composition in the rat model of Type 1 Diabetes.
methodsMale Wistar rats were randomly assigned into four groups: healthy animals which received control diet (CD) or pistachio diet (PD), and diabetic animals which received control diet (DCD) or pistachio diet (DPD) for 4 weeks. Plasma biochemical parameters were determined and histological examination of liver and pancreas was performed at the end of the dietary intervention. Adherent intestinal microbiota populations in jejunum, ileum, caecum and colon were analyzed. Fecal microbiota populations at the beginning and the end of the study were determined by microbiological analysis and 16S rRNA sequencing.
resultsDiabetic animals of both groups exhibited high plasma glucose and low insulin concentrations, as well as characteristic pancreatic lesions. Pistachio supplementation significantly increased lactobacilli and bifidobacteria populations in jejunum, ileum and caecum (
conclusionDietary pistachio restored normal flora and enhanced the presence of beneficial microbes in the rat model of streptozotocin-induced diabetes.
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