Evidence map›Paper›PMID 32812824›Full record

Trial reportNutrition and cancer2021

Excess Body Weight and Cancer-Related Fatigue, Systemic Inflammation, and Serum Lipids in Breast Cancer Survivors.

Julia E Inglis, Amber S Kleckner, Po-Ju Lin, Nikesha J Gilmore, Eva Culakova, Amy C VanderWoude, Karen M Mustian, I Diana Fernandez, Richard F Dunne, Jeremy Deutsch and 1 more

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrition and cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02352779 (Feasibility of Omega-3 Supplementation for Cancer-Related Fatigue), which is not on this map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02352779 nacompletednot on this map

Feasibility of Omega-3 Supplementation for Cancer-Related Fatigue

TypeinterventionalSponsorGary MorrowRan2015 to 2016Enrolled108ConditionsBreast Carcinoma, Cancer, FatigueArmsOmega-3 Fatty Acid, Placebo, Questionnaire Administration, Laboratory Biomarker Analysis
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Article
  7. The relationship between the latent profiles of cancer-related fatigue characteristics and exercise adherence in colorectal cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  8. Review
  9. Development and validation of a machine learning model to predict moderate-to-severe cancer-related fatigue in breast cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  10. Article
  11. Article
  12. Metabolic underpinnings of cancer-related fatigue.American journal of physiology. Endocrinology and metabolism · 2024
    Review
  13. Article
  14. Article
  15. Article
  16. Radiotherapy-induced fatigue in Palestinian breast cancer survivors.Health psychology and behavioral medicine · 2024
    Article
  17. Review
  18. Article
  19. Disparities in physical activity in adolescent and young adult cancer survivors.Journal of cancer survivorship : research and practice · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Julia E InglisDepartment of Public and Community Health, Liberty University, Lynchburg, VA, USA.
Amber S KlecknerDepartment of Surgery, University of Rochester Medical Center (URMC), Rochester, NY, USA.
Po-Ju LinDepartment of Surgery, University of Rochester Medical Center (URMC), Rochester, NY, USA.
Nikesha J GilmoreDepartment of Surgery, University of Rochester Medical Center (URMC), Rochester, NY, USA.
Eva CulakovaDepartment of Surgery, University of Rochester Medical Center (URMC), Rochester, NY, USA.
Amy C VanderWoudeCancer Research Consortium of West Michigan, Grand Rapids, MI, USA.
Karen M MustianDepartment of Surgery, University of Rochester Medical Center (URMC), Rochester, NY, USA.
I Diana FernandezDepartment of Public Health Sciences, University of Rochester Medical Center (URMC), Rochester, NY, USA.
Richard F DunneDepartment of Medicine, University of Rochester Medical Center (URMC), Rochester, NY, USA.
Jeremy DeutschCancer Center of Kansas, Wichita, KS, USA.
Luke J PepponeDepartment of Surgery, University of Rochester Medical Center (URMC), Rochester, NY, USA.
University of Rochester Medical Center · USCancer Center of Kansas · USLiberty University · USMichigan Cancer Research Consortium · US

Funding

URCC NCORP Research BaseUG1CA189961 · NCI · UNIVERSITY OF ROCHESTER · PI Michelle C Janelsins, KAREN M. MUSTIAN · 2014 to 2026
$67.7M
Cancer Control Research Training Curriculum (R25T)R25CA102618 · NCI · UNIVERSITY OF ROCHESTER · PI JANELSINS, MICHELLE C, MORROW, GARY R · 2004 to 2018
$6.7M
Clinical and Translational Cancer Control Research Training ProgramT32CA102618 · NCI · UNIVERSITY OF ROCHESTER · PI Michelle C Janelsins, Gary R Morrow · 2019 to 2026
$2.7M
Management of Cancer-Treatment-Induced Bone LossK07CA168911 · NCI · UNIVERSITY OF ROCHESTER · PI PEPPONE, LUKE JOSEPH · 2013 to 2017
$724k
Feasibility of Omega-3 Supplementation for Cancer-related FatigueR03CA175599 · NCI · UNIVERSITY OF ROCHESTER · PI PEPPONE, LUKE JOSEPH · 2014 to 2015
$154k
NCI NIH HHS K07 CA168911NCI NIH HHS R03 CA175599NCI NIH HHS R25 CA102618NCI NIH HHS T32 CA102618NCI NIH HHS UG1 CA189961
6 · The paper itself

Abstract

backgroundCancer-related fatigue (CRF) is a common side effect impacting breast cancer survivors. Research points to a relationship between obesity and CRF in breast cancer survivors related to elevated systemic inflammation and metabolic alterations.

methodsThis cross-sectional study examined the relationship of obesity to CRF, inflammatory markers and serum lipids through a secondary analysis of a nationwide randomized controlled trial. Breast cancer survivors with CRF were categorized based on BMI category. Symptoms of CRF, inflammatory markers and serum fatty acids were assessed among groups.

resultsThere were 105 breast cancer survivors in the analysis. BMI was positively associated with CRF based on MFSI General (

conclusionsObese breast cancer survivors had greater levels of CRF, inflammatory markers and certain fatty acids. Inflammatory markers and fatty acids were not found to have any mediating or positive association with CRF variables in this analysis. NCT02352779.

Indexed as

Breast NeoplasmsCancer SurvivorsFatty Acids, Omega-3Cross-Sectional StudiesFatigueFemaleHumansInflammationObesityFatty Acids, Omega-3

Identifiers

PMID32812824
PMCPMC7904100
OpenAlexW3071167424

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.