Observational studyJournal of the American Heart Association2020
Change of Health-Related Quality of Life Over Time and Its Association With Patient Outcomes in Patients With Heart Failure.
Observational study in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 49 citations in OpenAlex.
- Left atrial stiffness, exercise intolerance and injury biomarkers predict adverse outcomes in patients with heart failure with preserved ejection fraction.NPJ cardiovascular health · 2026Article
- Relative Contributions of Functional Capacity and Inflammatory Activity to Quality of Life in Heart Failure with Preserved Ejection Fraction.Biomedicines · 2026Article
- Health-related quality of life trajectories and loss of independence among community-dwelling older adults.GeroScience · 2026Article
- Patient-Reported Health Status Among Patients With Heart Failure With Improved Ejection Fraction.Journal of the American Heart Association · 2026Article
- Impact of Comorbidity Clusters on Quality of Life in Chronic Heart Failure.Vascular health and risk management · 2026Article
- Independent predictors of quality of life in patients with chronic heart failure.Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina) · 2025Article
- Health-related quality of life across heart failure categories: associations with clinical characteristics and outcomes.ESC heart failure · 2025Article
- Trajectory of health-related quality of life during and after hospitalisation due to worsening of heart failure.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- PROMIS fatigue scores are moderately correlated with heart failure severity in pediatrics.JHLT open · 2024Article
- Review
- Global epidemiology of heart failure.Nature reviews. Cardiology · 2024Review
- Prognostic value of quality of life and functional status in patients with heart failure: a systematic review and meta-analysis.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2024Review
- Changes over time in patient-reported outcomes in patients with heart failure.ESC heart failure · 2024Article
- Differences in Health-Related Quality of Life among Patients with Heart Failure.Medicina (Kaunas, Lithuania) · 2024Review
- Article
- Patient and parent-reported outcomes in paediatric ventricular assist device support: a multi-center ACTION learning network feasibility and pilot experience.Cardiology in the young · 2023Article
- Health-related quality of life among transthyretin amyloid cardiomyopathy patients.ESC heart failure · 2023Article
- Five-year follow-up mortality prognostic index for colorectal patients.International journal of colorectal disease · 2023Observational
- Quality of life in patients with heart failure and improved ejection fraction: one-year changes and prognosis.ESC heart failure · 2022Review
- Predictors and outcomes of quality of life in elderly patients with heart failure.American heart journal plus : cardiology research and practice · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Improving health-related quality of life is an important goal in the management of patients with heart failure (HF). Defining health-related quality of life changes over time in patients with HF with preserved (HFpEF) or reduced ejection fraction and showing their association with other important clinical events could support the use of health-related quality of life as a measure of quantifying HF care. Methods and Results In the Alberta HEART (Heart Failure Aetiology and Analysis Team) cohort (n=621), patients were categorized into 4 subgroups: healthy controls (n=98), at risk (n=163), HFpEF (n=191), and HF with reduced ejection fraction (n=169). The change of the Kansas City Cardiomyopathy Questionnaire (KCCQ), EuroQOL 5 dimensions, and Functional Assessment of Cancer Therapy-Anemia over 12 months, and its association with a composite of death or rehospitalization within 3 years were assessed. At baseline, the KCCQ overall summary score was 73 (interquartile range, 53-86) in HFpEF and 78 (interquartile range, 56-90) in HF with reduced ejection fraction (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.