Evidence map›Paper›PMID 32812211›Full record

ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2021

Promising application of the SsCBF ELISA test to monitor the therapeutic response of feline sporotrichosis caused by Sporothrix brasiliensis from Brazilian epidemics.

Vivian S Baptista, Gabriele Barros Mothé, Giulia M P Santos, Carla Stefany I Melivilu, Thayana O Santos, Emylli D Virginio, Pãmella A de Macêdo-Sales, Márcia Ribeiro Pinto, Ricardo Luiz D Machado, Elisabeth M S Rocha and 2 more

Open access · greenAbstract readEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Guideline for the management of feline sporotrichosis caused by Sporothrix brasiliensis and literature revision.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021
    Review
  6. Special issue on sporotrichosis: challenges to deal with the new emerging pathogenic species.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Vivian S BaptistaCenter for Microorganisms' Investigation, Biomedical Institute, Federal Fluminense University, Block E, Outeiro de São João Batista, s/n, Centro, Niterói, RJ, 24020 140, Brazil.
Gabriele Barros MothéCenter for Microorganisms' Investigation, Biomedical Institute, Federal Fluminense University, Block E, Outeiro de São João Batista, s/n, Centro, Niterói, RJ, 24020 140, Brazil.
Giulia M P SantosCenter for Microorganisms' Investigation, Biomedical Institute, Federal Fluminense University, Block E, Outeiro de São João Batista, s/n, Centro, Niterói, RJ, 24020 140, Brazil.
Carla Stefany I MeliviluCenter for Microorganisms' Investigation, Biomedical Institute, Federal Fluminense University, Block E, Outeiro de São João Batista, s/n, Centro, Niterói, RJ, 24020 140, Brazil.
Thayana O SantosLaboratory of Cellular Mycology and Proteomics, Rio de Janeiro State University, Rio de Janeiro, RJ, Brazil.
Emylli D VirginioLaboratory of Cellular Mycology and Proteomics, Rio de Janeiro State University, Rio de Janeiro, RJ, Brazil.
Pãmella A de Macêdo-SalesCenter for Microorganisms' Investigation, Biomedical Institute, Federal Fluminense University, Block E, Outeiro de São João Batista, s/n, Centro, Niterói, RJ, 24020 140, Brazil.
Márcia Ribeiro PintoCenter for Microorganisms' Investigation, Biomedical Institute, Federal Fluminense University, Block E, Outeiro de São João Batista, s/n, Centro, Niterói, RJ, 24020 140, Brazil.
Ricardo Luiz D MachadoCenter for Microorganisms' Investigation, Biomedical Institute, Federal Fluminense University, Block E, Outeiro de São João Batista, s/n, Centro, Niterói, RJ, 24020 140, Brazil.
Elisabeth M S RochaCenter for Microorganisms' Investigation, Biomedical Institute, Federal Fluminense University, Block E, Outeiro de São João Batista, s/n, Centro, Niterói, RJ, 24020 140, Brazil.
Leila Maria Lopes-BezerraLaboratory of Cellular Mycology and Proteomics, Rio de Janeiro State University, Rio de Janeiro, RJ, Brazil.
Andréa Regina S BaptistaCenter for Microorganisms' Investigation, Biomedical Institute, Federal Fluminense University, Block E, Outeiro de São João Batista, s/n, Centro, Niterói, RJ, 24020 140, Brazil. andrearegina@id.uff.br.ORCID https://orcid.org/0000-0002-0461-7521
Universidade Federal Fluminense · BRUniversidade do Estado do Rio de Janeiro · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 308097/2016-5Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Finance code 001Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E-26/010.001882/2014PROEXT/MEC non-aplicable
6 · The paper itself

Abstract

Sporotrichosis zoonotic transmission by cats has obtained hyperendemic magnitude in Rio de Janeiro, Brazil. Atypical cases, relapses, and reinfections as well as reduced diagnostic sensitivity of conventional methods have been reported. Previously, the anti-SsCBF enzyme-linked immunosorbent assay (ELISA) test was shown to be useful as a diagnostic tool for human sporotrichosis. Effective diagnosis and treatment are critical to interrupt the chain of transmission of this major pathogen in Brazilian Public Health. To evaluate its applicability for feline sporotrichosis diagnosis and/or therapeutic follow-up, 15 domestic cats from Rio de Janeiro were clinically and laboratory monitored by cytopathology, culture, Sporothrix genotyping, and anti-SsCBF IgG levels. Subsequently, animals were divided into satisfactory and non-satisfactory therapeutic responders. Averages of antibody serum levels obtained for diagnosis (first consultation) compared with the levels found after follow-up (last consultation) were significantly different in both groups (p = 0.0002 and p = 0.038, respectively). We conclude that the SsCBF ELISA test can predict feline sporotrichosis therapeutic responses even for animals with distinct clinical evolutions.

Indexed as

AnimalsAntibodies, FungalBrazilCat DiseasesCatsDrug MonitoringEnzyme-Linked Immunosorbent AssaySporothrixSporotrichosisAntibodies, FungalAntifungal treatmentFelis catusSerologySporothichosisSporothrix brasiliensisZoonoses

Identifiers

PMID32812211
PMCPMC7966570
OpenAlexW3064461963

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.