Evidence map›Paper›PMID 32812166›Full record

ArticleBiogerontology2020

Exercise combined with a probiotics treatment alters the microbiome, but moderately affects signalling pathways in the liver of male APP/PS1 transgenic mice.

Tímea Téglás, Dóra Ábrahám, Mátyás Jókai, Saki Kondo, Rezieh Mohammadi, János Fehér, Dóra Szabó, Marta Wilhelm, Zsolt Radák

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biogerontology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 39 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Tímea TéglásResearch Center for Molecular Exercise Science, University of Physical Education, Alkotas str. 44, Budapest, 1123, Hungary.
Dóra ÁbrahámResearch Center for Molecular Exercise Science, University of Physical Education, Alkotas str. 44, Budapest, 1123, Hungary.
Mátyás JókaiResearch Center for Molecular Exercise Science, University of Physical Education, Alkotas str. 44, Budapest, 1123, Hungary.
Saki KondoResearch Center for Molecular Exercise Science, University of Physical Education, Alkotas str. 44, Budapest, 1123, Hungary.
Rezieh MohammadiResearch Center for Molecular Exercise Science, University of Physical Education, Alkotas str. 44, Budapest, 1123, Hungary.
János FehérOphthalmology Unit, NESMOS Department, Sant'Andrea Hospital, Faculty of Medicine and Psychology, "Sapienza" University of Rome, Rome, Italy.
Dóra SzabóSemmelweis University, Budapest, Hungary.
Marta WilhelmInstitute of Sport Sciences and Physical Education, Faculty of Science, University of Pécs, Pecs, 2020, Hungary.
Zsolt RadákResearch Center for Molecular Exercise Science, University of Physical Education, Alkotas str. 44, Budapest, 1123, Hungary. radak@tf.hu.ORCID 0000-0003-1297-6804
Hungarian University of Sports Science · HUWaseda University · JPSapienza University of Rome · ITSemmelweis University · HUTokyo University of the Arts · JP

Funding

Hungarian Scientific Research Fund 112810Hungarian Scientific Research Fund 126823Hungarian Scientific Research Fund TUDFO/51757/2019-ITM
6 · The paper itself

Abstract

It has been demonstrated that physical exercise and probiotic supplementation delay the progress of Alzheimer's Disease (AD) in male APP/PS1

Indexed as

Alzheimer DiseaseLiverMicrobiotaPhysical Conditioning, AnimalProbioticsSignal TransductionAmyloid beta-PeptidesAmyloid beta-Protein PrecursorAnimalsDisease Models, AnimalHippocampusMaleMiceMice, Inbred C57BLMice, TransgenicPresenilin-1Amyloid beta-PeptidesAmyloid beta-Protein PrecursorPresenilin-1Alzheimer’s diseaseExerciseLiverMetabolismMicrobiomeProbiotics

Identifiers

PMID32812166
PMCPMC7541368
OpenAlexW3066502630

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.