Observational studyWorld journal of surgery2020
Gender Differences in Postoperative Pain, Nausea and Vomiting After Elective Laparoscopic Cholecystectomy.
Observational study in World journal of surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 29 citations in OpenAlex.
- Sex-related differences in pain following posterior spinal fusion for adolescent idiopathic scoliosis: a retrospective cohort study.Spine deformity · 2026Article
- Comment on: Impact of low-pressure pneumoperitoneum and deep neuromuscular blockade on surgeon satisfaction and patient outcomes in laparoscopic cholecystectomy patients: A prospective randomised controlled study.Journal of minimal access surgery · 2026Article
- Perioperative Anxiety and Stress Cortisol on Postoperative Pain: Pharmacological and Non-Pharmacological Management Strategies.Journal of surgery and research · 2026Article
- Article
- Analgesic Differences in Males and Females After Third Molar Surgery: A Subgroup Analysis of the OARS Randomized Clinical Trial.JAMA network open · 2025Article
- Article
- Postoperative Analgesic Effects of Anterior Quadratus Lumborum Block vs Intravenous Analgesics Administered to Donors and Recipients in Renal Transplantation Surgery: A Prospective Cohort Study.Annals of transplantation · 2025Article
- Article
- Sex-related differences in postoperative patient-reported outcomes among lung cancer patients: a multicenter cohort study.BMC cancer · 2025Observational
- The Effect of Maropitant, Ondansetron and Metoclopramide on Dexmedetomidine-Induced Vomiting in Cats.Veterinary medicine and science · 2025Article
- Sex Disparities in Opioid Prescription and Administration on a Hospital Medicine Service.Journal of general internal medicine · 2024Article
- Factors associated with postoperative nausea and vomiting after laparoscopic cholecystectomy at the National Referral Hospital, Bhutan: a cross-sectional study.BMC anesthesiology · 2024Article
- Association of Sex Differences on Weight Loss and Complications Following Bariatric Surgery.The Journal of surgical research · 2024Article
- Differences in Postoperative Pain, Nausea, and Vomiting After Elective Laparoscopic Cholecystectomy in Premenopausal and Postmenopausal Mexican Women.World journal of surgery · 2022Article
- Postoperative Vomiting Following Laparoscopic Cholecystectomy Is Associated with Intraoperative Fluid Administration: A Retrospective Cohort Study.International journal of environmental research and public health · 2021Article
- Description and Comparison of Acute Pain Characteristics After Laparoscope-Assisted Vaginal Hysterectomy, Laparoscopic Myomectomy and Laparoscopic Adnexectomy.Journal of pain research · 2021Article
Corrections and comments
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Authors and funding
15 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough reports suggest that pain and postoperative nausea and vomiting (PONV) may be more frequent in women, the evidence is inconsistent. The objective of this study was to investigate whether women are more sensitive to pain and PONV after laparoscopic cholecystectomy (LC).
methodsA total of 370 women and 275 men were included in a retrospective cohort study. All underwent LC under standardized general anesthesia. The variables analyzed included clinical and anthropometric parameters. End points were the incidence of nausea, vomiting, pain, and the requirement for additional pain relievers and antiemetics to control these.
resultsThe women were younger and had lower body weight than the men (p < 0.001). Body mass index was within the normal range for 50% of women and 30% of men (p < 0.001). Pain was more common in women at 1, 6, 12 and 24 h after surgery (p < 0.02). Narcotics in addition to the doses used to lessen pain intensity (p = 0.01) were required in 60 women and 19 men (p < 0.001). PONV was more frequent in women at 1 and 6 h after surgery (p < 0.01). Rescue antiemetics were required in 35 women and 11 men (p = 0.008). Hospital stay was shorter for men (p < 0.001). Four patients in each group developed postoperative complications (p = 0.14). There was no mortality.
conclusionsEarly postoperative pain, nausea and vomiting after LC were more common in women, who more frequently required analgesic and antiemetic rescue medication.
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