Evidence map›Paper›PMID 32811851›Full record

ArticleScientific reports2020

Targeting cPLA

Gavin Pharaoh, Jacob L Brown, Kavithalakshmi Sataranatarajan, Parker Kneis, Jan Bian, Rojina Ranjit, Niran Hadad, Constantin Georgescu, Peter Rabinovitch, Qitao Ran and 5 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. iPLAScience advances · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Reactive oxygen species in the pathogenesis of sarcopenia.Free radical biology & medicine · 2025
    Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Gavin PharaohPhysiology Department, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Jacob L BrownAging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.
Kavithalakshmi SataranatarajanAging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.
Parker KneisAging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.
Jan BianAging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.
Rojina RanjitAging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.
Niran HadadReynolds Oklahoma Center on Aging, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Constantin GeorgescuGenes and Human Disease Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.
Peter RabinovitchDepartment of Pathology, University of Washington, Seattle, WA, USA.
Qitao RanDepartment of Cell Systems and Anatomy, UT Health San Antonio, San Antonio, TX, USA.
Jonathan D WrenGenes and Human Disease Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.
Willard FreemanPhysiology Department, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Michael KinterAging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.
Arlan RichardsonReynolds Oklahoma Center on Aging, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Holly Van RemmenPhysiology Department, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA. Holly-VanRemmen@omrf.org.
Oklahoma Medical Research Foundation · USUniversity of Oklahoma Health Sciences Center · USOklahoma City VA Medical Center · USSouth Texas Veterans Health Care System · USUniversity of Washington · US

Funding

Proteomics CoreP20GM103447 · NIGMS · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI Michael T Kinter · 2012 to 2026
$60.2M
PROJECT 3: Neuromuscular redox homeostasis in mice lacking SOD1 and aging wild type mice subcontract at University of LiverpoolP01AG051442 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BROOKS, SUSAN V · 2016 to 2020
$8.9M
GEROSCIENCE TRAINING PROGRAM IN OKLAHOMAT32AG052363 · NIA · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI Benjamin Francis Miller, William Edmund Sonntag · 2017 to 2026
$3.6M
Defining the relative roles of pre- and post-synaptic events in the initiation and progression of sarcopeniaR01AG050676 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BROOKS, SUSAN V, VAN REMMEN, HOLLY · 2016 to 2020
$3.3M
BLRD VA I01 BX002595BLRD VA IK6 BX005234NIA NIH HHS P01 AG051442NIA NIH HHS R01 AG050676NIA NIH HHS R01AG050676NIA NIH HHS T32 AG052363NIGMS NIH HHS P20 GM103447
6 · The paper itself

Abstract

Defects in neuromuscular innervation contribute significantly to the age-related decline in muscle mass and function (sarcopenia). Our previous studies demonstrated that denervation induces muscle mitochondrial hydroperoxide production (H

Indexed as

AnimalsCytosolElectron Transport Chain Complex ProteinsHydrogen PeroxideLipid PeroxidesMaleMiceMice, Inbred C57BLMitochondriaMitochondrial MembranesMuscle Fibers, SkeletalMuscle, SkeletalMuscular AtrophyOxidative StressPhospholipases A2SarcopeniaElectron Transport Chain Complex ProteinsHydrogen PeroxideLipid PeroxidesPhospholipases A2

Identifiers

PMID32811851
PMCPMC7435184
OpenAlexW3064388424

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.