SynthesisArchives of medical research2020
Diabetes Mellitus is Associated with Severe Infection and Mortality in Patients with COVID-19: A Systematic Review and Meta-analysis.
Synthesis in Archives of medical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
39 citing papers in PubMed, 6 syntheses or guidelines pooled it, 76 citations in OpenAlex.
- Pooled it
- Pre-existing health conditions and severe COVID-19 outcomes: an umbrella review approach and meta-analysis of global evidence.BMC medicine · 2021Pooled it
- Impact of diabetes mellitus on in-hospital mortality in adult patients with COVID-19: a systematic review and meta-analysis.Acta diabetologica · 2021Pooled it
- Risk phenotypes of diabetes and association with COVID-19 severity and death: a living systematic review and meta-analysis.Diabetologia · 2021Pooled it
- Quality of systematic reviews of COVID-19 in people with diabetes: A systematic review.Enfermeria clinicaPooled it
- [Quality of systematic reviews of COVID-19 in people with diabetes: A systematic review].Enfermeria clinicaPooled it
- Increased risk of poor clinical outcome in COVID-19 patients with diabetes mellitus and in-hospital mortality predictors: A retrospective cohort from a tertiary hospital in Indonesia.Endocrinology, diabetes & metabolism · 2023Article
- The Influence of SARS-CoV-2 Infection on Acute Myocardial Infarction Outcomes.Journal of clinical medicine · 2023Article
- Surgical management for hip fracture in a COVID-19 patient: A case report and literature review.Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association · 2023Review
- Prevalence and risk factors of COVID-19 infection, mortality, and post-infection lung fibrosis in patients with type 2 diabetes: a cross-sectional study.The Journal of international medical research · 2023Article
- Diabetes and deaths of COVID-19 patients: Systematic review of meta-analyses.Health sciences review (Oxford, England) · 2023Review
- The National Clinical Care Commission Report to Congress: Background, Methods, and Foundational Recommendations.Diabetes care · 2023Review
- Mitochondrial oxidative stress, mitochondrial ROS storms in long COVID pathogenesis.Frontiers in immunology · 2023Review
- Predictors of mortality in critically ill patients with COVID-19 and diabetes.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2023Article
- Practical infection control training for Victoria's aged care workforce at the time of COVID-19 pandemic: a community case study.Frontiers in public health · 2023Article
- Effect of COVID-19 vaccine on blood glucose metrics in Arabic people with type 1 diabetes.Frontiers in endocrinology · 2023Article
- Barthel's Index: A Better Predictor for COVID-19 Mortality Than Comorbidities.Tuberculosis and respiratory diseases · 2022Article
- Telemetric Assessment of Continuous Positive Airways Pressure (CPAP) Effectiveness and Adherence in Obstructive Sleep Apnea during COVID-19 Pandemic.Biomedicines · 2022Article
- Type 1 and type 2 diabetes mellitus: Clinical outcomes due to COVID-19. Protocol of a systematic literature review.PloS one · 2022Article
- Ethnicity and other COVID-19 death risk factors in Mexico.Archives of medical science : AMS · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimCurrently, the number of patients with coronavirus disease 2019 (COVID-19) infection is increasing rapidly worldwide. In this study, we aimed to assess whether diabetes mellitus (DM) would increase the risk of severe infection and death in patients with COVID-19.
methodsWe systematically searched the PubMed, Web of Science, MedRxiv and COVID-19 academic research communication platform for studies reporting clinical severity and/or overall mortality data on DM in patients with COVID-19 published up to July 10, 2020. The primary outcome was to compare the severe infection rate and mortality rate in COVID-19 patients with and without DM, and to calculate the odds ratio (OR) and 95% confidence interval (CI).
resultsA total of 76 studies involving 31,067 patients with COVID-19 were included in our meta-analysis. COVID-19 patients with DM had higher severe infection and case-mortality rates compared with those without DM (21.4 vs. 10.6% and 28.5 vs. 13.3%, respectively, all p <0.01). COVID-19 patients with DM were at significantly elevated risk of severe infection (OR = 2.38, 95% CI: 2.05-2.78, p <0.001) and mortality (OR = 2.21, 95% CI: 1.83-2.66, p <0.001).
conclusionDM is associated with increased risk of severe infection and higher mortality in patients with COVID-19. Our study suggests that clinicians should pay more attention to the monitoring and treatment of COVID-19 patients with DM.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.