Evidence map›Paper›PMID 32811570›Full record

ArticleCancer imaging : the official publication of the International Cancer Imaging Society2020

Prediction of microvascular invasion of hepatocellular carcinoma: value of volumetric iodine quantification using preoperative dual-energy computed tomography.

Taek Min Kim, Jeong Min Lee, Jeong Hee Yoon, Ijin Joo, Sae-Jin Park, Sun Kyung Jeon, Bernhard Schmidt, Sedlmair Martin

Abstract readEvaluation Study
In one paragraph

Article in Cancer imaging : the official publication of the International Cancer Imaging Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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  12. Spectral CT: Current Liver Applications.Diagnostics (Basel, Switzerland) · 2023
    Review
  13. Article
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  15. [Research progress of microvascular invasion in hepatocellular carcinoma].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2022
    Review
  16. Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Taek Min KimDepartment of Radiology, Seoul National University Hospital, Seoul, South Korea.
Jeong Min LeeDepartment of Radiology, Seoul National University Hospital, Seoul, South Korea. jmlshy2000@gmail.com.ORCID http://orcid.org/0000-0003-0561-8777
Jeong Hee YoonDepartment of Radiology, Seoul National University Hospital, Seoul, South Korea.
Ijin JooDepartment of Radiology, Seoul National University Hospital, Seoul, South Korea.
Sae-Jin ParkDepartment of Radiology, Seoul National University Hospital, Seoul, South Korea.
Sun Kyung JeonDepartment of Radiology, Seoul National University Hospital, Seoul, South Korea.
Bernhard SchmidtResearch and development department, Siemens Healthineers, Forchheim, Germany.
Sedlmair MartinResearch and development department, Siemens Healthineers, Forchheim, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo investigate the potential value of volumetric iodine quantification using preoperative dual-energy computed tomography (DECT) for predicting microvascular invasion (MVI) of hepatocellular carcinoma (HCC).

methodsThis retrospective study included patients with single HCC treated through surgical resection who underwent preoperative DECT. Quantitative DECT features, including normalized iodine concentration (NIC) to the aorta and mixed-energy CT attenuation value in the arterial phase, were three-dimensionally measured for peritumoral and intratumoral regions: (i) layer-by-layer analysis for peritumoral layers (outer layers 1 and 2; numbered in close order from the tumor boundary) and intratumoral layers (inner layers 1 and 2) with 2-mm layer thickness and (ii) volume of interest (VOI)-based analysis with different volume coverage (tumor itself; VOI

resultsA total of 36 patients (24 men, mean age 59.9 ± 8.5 years) with MVI (n = 14) and without MVI (n = 22) were included. HCCs with MVI showed significantly higher NICs of outer layer 1, outer layer 2, VOI

conclusionsVolumetric iodine quantification of peritumoral and intratumoral regions in arterial phase using DECT may help predict the MVI of HCC.

Indexed as

AdultAgedCarcinoma, HepatocellularCone-Beam Computed TomographyFemaleHumansIodineLiver NeoplasmsMaleMicrovesselsMiddle AgedNeoplasm InvasivenessPreoperative PeriodRadiography, Dual-Energy Scanned ProjectionIodineDual-energy CTHepatocellular carcinomaIodine concentrationIodine quantificationMicrovascular invasionPeritumoral enhancement

Identifiers

PMID32811570
PMCPMC7433153

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.