Observational studyScandinavian journal of trauma, resuscitation and emergency medicine2020
Validation of a point-of-care capillary lactate measuring device (Lactate Pro 2).
Observational study in Scandinavian journal of trauma, resuscitation and emergency medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 32 citations in OpenAlex.
- Cardiorespiratory and metabolic stress responses to acute high-intensity interval training anchored to critical power or maximal heart rate.Scientific reports · 2025Trial
- Short-term creatine supplementation enhances strength, reduces fatigue, and accelerates recovery in resistance-trained athletes: a double-blind, randomized, crossover trial.Journal of the International Society of Sports Nutrition · 2025Trial
- Menthol Mouth Rinsing Maintains Relative Power Production during Three-Minute Maximal Cycling Performance in the Heat Compared to Cold Water and Placebo Rinsing.International journal of environmental research and public health · 2022Trial
- Unlocking high-intensity performance thresholds through ventilatory signatures in the ECG.Scientific reports · 2026Article
- Validation of a novel handheld lactate analyzer reveals concentration-dependent bias compared with a laboratory reference device.Biology open · 2026Article
- Training-Fuel Coupling (TFC): A Molecular Sports Nutrition Framework for Energy Availability, Chrono-Nutrition, and Performance Optimization.Nutrients · 2026Review
- Recent advances in early screening and diagnosis of sepsis: a narrative review.Frontiers in cellular and infection microbiology · 2026Review
- Comparison of non-invasive strategies to drive fluid resuscitation in sepsis or septic shock: a meta-analysis of RCTs.Internal and emergency medicine · 2025Review
- Lactate Thresholds and Performance in Young Cross-Country Skiers Before and After the Competitive Season: Insights from Laboratory Roller-Ski Tests in Normoxic and Hypoxic Conditions.Sports (Basel, Switzerland) · 2025Article
- Power Output, Lactatemia, and Maximum Oxygen Consumption During a Specific Off-Water Incremental Test in International-Level Podium-Winner Kayak and Rowing Athletes.Journal of functional morphology and kinesiology · 2025Article
- Observational Analysis of Point-of-Care Lactate Plus™ Meter in Preclinical Trauma Models.Diagnostics (Basel, Switzerland) · 2024Article
- Effect of active recovery using individual maximum exercise capacity: a pilot study.Journal of physical therapy science · 2024Article
- The predictive value of serum lactate to forecast injury severity in trauma-patients increases taking age into account.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024Article
- The effect of menthol rinsing before intermittent exercise on physiological, physical, and thermo-behavioral responses of male football referees in hot and humid environment.Frontiers in sports and active living · 2024Article
- The Effects of 24-h Fasting on Exercise Performance and Metabolic Parameters in a Pilot Study of Female CrossFit Athletes.Nutrients · 2023Article
- Menthol mouth rinsing and performance in elite football referees in the heat: A study protocol for a randomized crossover trial.Contemporary clinical trials communications · 2023Article
- Comparison between Capillary and Serum Lactate Levels in Predicting Short-Term Mortality of Septic Patients at the Emergency Department.International journal of molecular sciences · 2023Observational
- Acute response of biomarkers in plasma from capillary blood after a strenuous endurance exercise bout.European journal of applied physiology · 2023Article
- Accuracy of a point-of-care blood lactate measurement device in a prehospital setting.Journal of clinical monitoring and computing · 2022Article
- Elevated serum lactate levels and age are associated with an increased risk for severe injury in trauma team activation due to trauma mechanism.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundThe measurement of lactate in emergency medical services has the potential for earlier detection of shock and can be performed with a point-of-care handheld device. Validation of a point-of-care handheld device is required for prehospital implementation.
aimThe primary aim was to validate the accuracy of Lactate Pro 2 in healthy volunteers and in haemodynamically compromised intensive care patients. The secondary aim was to evaluate which sample site, fingertip or earlobe, is most accurate compared to arterial lactate.
methodsArterial, venous and capillary blood samples from fingertips and earlobes were collected from intensive care patients and healthy volunteers. Arterial and venous blood lactate samples were analysed on a stationary hospital blood gas analyser (ABL800 Flex) as the reference device and compared to the Lactate Pro 2. We used the Bland-Altman method to calculate the limits of agreement and used mixed effect models to compare instruments and sample sites. A total of 49 intensive care patients with elevated lactate and 11 healthy volunteers with elevated lactate were included.
resultsThere was no significant difference in measured lactate between Lactate Pro 2 and the reference method using arterial blood in either the healthy volunteers or the intensive care patients. Capillary lactate measurement in the fingertip and earlobe of intensive care patients was 47% (95% CI (29 to 68%), p < 0.001) and 27% (95% CI (11 to 45%), p < 0.001) higher, respectively, than the corresponding arterial blood lactate. In the healthy volunteers, we found that capillary blood lactate in the fingertip was 14% higher than arterial blood lactate (95% CI (4 to 24%), p = 0.003) and no significant difference between capillary blood lactate in the earlobe and arterial blood lactate.
conclusionOur results showed that the handheld Lactate Pro 2 had good agreement with the reference method using arterial blood in both intensive care patients and healthy volunteers. However, we found that the agreement was poorer using venous blood in both groups. Furthermore, the earlobe may be a better sample site than the fingertip in intensive care patients.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.