Evidence map›Paper›PMID 32811204›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2020

Synthesis, anticancer evaluation and molecular docking studies of new benzimidazole- 1,3,4-oxadiazole derivatives as human topoisomerase types I poison.

Ulviye Acar Çevik, Begüm Nurpelin Sağlık, Derya Osmaniye, Serkan Levent, Betül Kaya Çavuşoğlu, Abdullah Burak Karaduman, Özlem Atlıd, Özlem Atlı Eklioğlu, Zafer Asım Kaplancıklı

Open access · goldAbstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 53 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ulviye Acar ÇevikDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey.ORCID https://orcid.org/0000-0003-1879-1034
Begüm Nurpelin SağlıkDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey.ORCID https://orcid.org/0000-0002-0151-6266
Derya OsmaniyeDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey.ORCID https://orcid.org/0000-0002-0499-436X
Serkan LeventDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey.ORCID https://orcid.org/0000-0003-3692-163X
Betül Kaya ÇavuşoğluDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Zonguldak Bülent Ecevit University, Zonguldak, Turkey.ORCID https://orcid.org/0000-0001-8270-4949
Abdullah Burak KaradumanDepartment of Pharmaceutical Toxicology, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey.ORCID https://orcid.org/0000-0002-0434-1334
Özlem AtlıdDepartment of Pharmaceutical Toxicology, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey.ORCID https://orcid.org/0000-0002-6131-3399
Özlem Atlı EklioğluDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey.ORCID https://orcid.org/0000-0001-8815-153X
Zafer Asım KaplancıklıDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey.ORCID https://orcid.org/0000-0003-2252-0923
Anadolu University · TRBülent Ecevit University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, some benzimidazole-oxadiazole derivatives were synthesised and tested for their

Indexed as

Molecular Docking SimulationAnimalsAntineoplastic AgentsCell LineCell ProliferationDNA Topoisomerases, Type IDose-Response Relationship, DrugDrug Screening Assays, AntitumorHumansMiceMolecular StructureStructure-Activity RelationshipTopoisomerase I InhibitorsAntineoplastic AgentsDNA Topoisomerases, Type ITopoisomerase I Inhibitors1,3,4-oxadiazoleanticancerBenzimidazoleDNA Topo IHoechst 33342

Identifiers

PMID32811204
PMCPMC7470102
OpenAlexW3056535081

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.