Evidence map›Paper›PMID 32810927›Full record

ArticleFEBS open bio2020

A label-free impedance assay in endothelial cells differentiates the activation and desensitization properties of clinical S1P

Patrick Grailhe, Asma Boutarfa-Madec, Philippe Beauverger, Philip Janiak, Ashfaq A Parkar

Open access · goldAbstract read
In one paragraph

Article in FEBS open bio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Patrick GrailheDiabetes and Cardiovascular Research, Sanofi R&D, Chilly-Mazarin, France.ORCID 0000-0002-5925-1264
Asma Boutarfa-MadecDiabetes and Cardiovascular Research, Sanofi R&D, Chilly-Mazarin, France.
Philippe BeauvergerDiabetes and Cardiovascular Research, Sanofi R&D, Chilly-Mazarin, France.
Philip JaniakDiabetes and Cardiovascular Research, Sanofi R&D, Chilly-Mazarin, France.
Ashfaq A ParkarDiabetes and Cardiovascular Research, Sanofi US Services, Bridgewater, NJ, USA.
Sanofi (France) · FRSanofi (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sphingosine-1 phosphate receptor-1 (S1P

Indexed as

AcetatesAzetidinesBenzyl CompoundsElectric ImpedanceEndothelial CellsHumansHuman Umbilical Vein Endothelial CellsIndansLymphocytesMultiple SclerosisOxadiazolesPyrimidinesSignal TransductionSphingosine-1-Phosphate ReceptorsThiazolesAcetatesAzetidinesBenzyl CompoundsIndansOxadiazolesozanimodponesimodPyrimidinesS1PR1 protein, humansiponimodSphingosine-1-Phosphate ReceptorsThiazolesdesensitizationendotheliumimpedanceS1P1SAR247799siponimod

Identifiers

PMID32810927
PMCPMC7530392
OpenAlexW3062757265

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.