Evidence map›Paper›PMID 32810785›Full record

ReviewCurrent opinion in virology2020

T lymphocyte responses to flaviviruses - diverse cell populations affect tendency toward protection and disease.

Luis Alberto Sanchez Vargas, Anuja Mathew, Alan L Rothman

Abstract readReview
In one paragraph

Review in Current opinion in virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Observational
  2. Cellular Immune Response in Horses After West Nile Neuroinvasive Disease.Animals : an open access journal from MDPI · 2025
    Article
  3. Article
  4. Article
  5. Mucosal Vaccination: A Promising Alternative Against Flaviviruses.Frontiers in cellular and infection microbiology · 2022
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Luis Alberto Sanchez VargasInstitute for Immunology and Informatics and Department of Cell and Molecular Biology, University of Rhode Island, 80 Washington Street, Providence, RI 02903 USA.
Anuja MathewInstitute for Immunology and Informatics and Department of Cell and Molecular Biology, University of Rhode Island, 80 Washington Street, Providence, RI 02903 USA.
Alan L RothmanInstitute for Immunology and Informatics and Department of Cell and Molecular Biology, University of Rhode Island, 80 Washington Street, Providence, RI 02903 USA. Electronic address: alan_rothman@uri.edu.

Funding

VIRAL DETERMINANTS OF SEVERE DENGUE DISEASEP01AI034533 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI ROTHMAN, ALAN L · 1994 to 2022
$42.0M
NIAID NIH HHS P01 AI034533
6 · The paper itself

Abstract

Dengue virus (DENV), Yellow Fever virus, West Nile virus, Japanese encephalitis virus and Zika virus are medically important flaviviruses transmitted to humans by mosquitoes and circulate in overlapping geographic areas. Cross-reactive immune responses have been demonstrated among the flaviviruses, particularly the four DENV serotypes. The immunological imprint left by a flavivirus infection can therefore have profound effects on the responses to subsequent infections. In this review we summarize recent research focusing on T cell responses to DENV using clinical samples from prospective cohort studies in Asia. These data suggest that durability of different T cell populations after natural infection or vaccination is an important consideration for the outcome of subsequent flavivirus exposures and we argue for continued investigation in the context of longitudinal cohort studies.

Indexed as

AnimalsAntibodies, ViralCross ReactionsCulicidaeFlavivirusFlavivirus InfectionsHumansT-LymphocytesAntibodies, Viral

Identifiers

PMID32810785
PMCPMC7655706

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.