Evidence map›Paper›PMID 32810513›Full record

ArticleNeurotoxicology2020

Associations of the Behavioral Assessment and Research System (BARS) neurobehavioral outcomes with attention problems in children living near coal ash storage sites.

Lonnie Sears, Clara G Sears, John V Myers, Guy N Brock, Kristina M Zierold

Open access · greenAbstract read
In one paragraph

Article in Neurotoxicology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Lonnie SearsDepartment of Pediatrics, University of Louisville, Louisville, Kentucky, USA. Electronic address: lonnie.sears@louisville.edu.
Clara G SearsDepartment of Epidemiology, Brown University, Providence, Rhode Island, USA. Electronic address: clara_sears@brown.edu.
John V MyersDepartment of Biomedical Informatics and Center for Biostatistics, The Ohio State University, Columbus, Ohio, USA. Electronic address: john.myers@osumc.edu.
Guy N BrockDepartment of Biomedical Informatics and Center for Biostatistics, The Ohio State University, Columbus, Ohio, USA. Electronic address: guy.brock@osumc.edu.
Kristina M ZieroldDepartment of Environmental Health Sciences, University of Alabama at Birmingham, Birmingham, Alabama, USA. Electronic address: kzierold@uab.edu.
The Ohio State University · USBrown University · USUniversity of Alabama at Birmingham · USUniversity of Louisville · US

Funding

Coal Ash and Neurobehavioral Symptoms in Children Aged 6-14 Years Old.R01ES024757 · NIEHS · UNIVERSITY OF LOUISVILLE · PI ZIEROLD, KRISTINA MARIE · 2015 to 2019
$2.8M
NIEHS NIH HHS R01 ES024757
6 · The paper itself

Abstract

Environmental exposures have been linked to childhood problems with overactivity, attention, and impulse control, and an increased risk of attention deficit hyperactivity disorder (ADHD) diagnosis. Two approaches to identify these types of exposure-related neurobehavioral problems include the use of computerized tests, such as the Behavioral Assessment and Research System (BARS), as well as the use of behavior rating scales. To assess comparability of these two types of measures, we analyzed data from 281 children aged 6 to 14 years enrolled in a 5-year research study investigating coal ash exposure and neurobehavioral health. All children lived in proximity of coal ash storage sites. We administered six computer tests from the BARS and obtained behavior measures from the parent-completed Child Behavior Checklist (CBCL) ADHD DSM oriented scale. BARS test performance was associated with age indicating that the tests could be used to evaluate neurodevelopmental changes over time or across a wide age range. Tests within the BARS including Continuous Performance (CPT) false alarm (standardized estimate 1.57, 95% confidence interval (CI) (0.67, 2.48), adjusted p = 0.006), Selective Attention (SAT) wrong count (standardized estimate 2.8, 95% CI (1.17, 4.44), adjusted p = 0.006), and SAT proportion correct (standardized estimate -2.45, 95% CI (-4.01, -0.88), adjusted p = 0.01) were associated with attention and impulse control problems on the CBCL after adjustment for multiple comparisons. Findings support that the BARS can contribute to research on environmental exposures by assessing subclinical behaviors related to ADHD such as sustained attention, impulse control, response inhibition, associative learning, and short-term memory. Future research can examine relationships of these BARS measures with biomarkers of neurotoxic exposures related to living near coal ash storage sites to better identify the potential risk for ADHD-related behaviors among children living near coal ash storage sites.

Indexed as

ChecklistNeuropsychological TestsWaste Disposal FacilitiesAdolescentAdolescent BehaviorAge FactorsAttentionAttention Deficit Disorder with HyperactivityChildChild BehaviorCoal AshCognitionEnvironmental ExposureFemaleHumansKentuckyCoal AshADHDBARSChildrenEnvironmental ExposureNeurobehavioral testsNeurotoxins

Identifiers

PMID32810513
PMCPMC7708521
OpenAlexW3049656806

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.