Evidence map›Paper›PMID 32810412›Full record

ArticleAnnals of the American Thoracic Society2021

Effect of Concomitant Azithromycin and Tobramycin Use on Cystic Fibrosis Pulmonary Exacerbation Treatment.

Jonathan D Cogen, Anna V Faino, Frankline Onchiri, Ronald L Gibson, Lucas R Hoffman, Matthew P Kronman, Margaret Rosenfeld, David P Nichols

Open access · greenAbstract read
In one paragraph

Article in Annals of the American Thoracic Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Drugs, Drugs, Drugs: Current Treatment Paradigms in Cystic Fibrosis Airway Infections.Journal of the Pediatric Infectious Diseases Society · 2022
    Review
  5. Antibiotic resistance in chronic respiratory diseases: from susceptibility testing to the resistome.European respiratory review : an official journal of the European Respiratory Society · 2022
    Review
  6. Association Between Number of Intravenous Antipseudomonal Antibiotics and Clinical Outcomes of Pediatric Cystic Fibrosis Pulmonary Exacerbations.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
  7. Update in Pediatrics 2020.American journal of respiratory and critical care medicine · 2021
    Article
  8. Article
  9. Resistance mechanisms and therapeutic strategies forTherapeutic advances in infectious disease
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jonathan D CogenDivision of Pulmonary and Sleep Medicine, Department of Pediatrics, Seattle Children's Hospital.
Anna V FainoChildren's Core for Biomedical Statistics, Seattle Children's Research Institute, and.
Frankline OnchiriChildren's Core for Biomedical Statistics, Seattle Children's Research Institute, and.
Ronald L GibsonDivision of Pulmonary and Sleep Medicine, Department of Pediatrics, Seattle Children's Hospital.
Lucas R HoffmanDivision of Pulmonary and Sleep Medicine, Department of Pediatrics, Seattle Children's Hospital.
Matthew P KronmanDivision of Infectious Diseases, Department of Pediatrics, University of Washington, Seattle, Washington.
Margaret RosenfeldDivision of Pulmonary and Sleep Medicine, Department of Pediatrics, Seattle Children's Hospital.
David P NicholsDivision of Pulmonary and Sleep Medicine, Department of Pediatrics, Seattle Children's Hospital.ORCID 0000-0001-8611-7960
Seattle Children's Hospital · USChildren’s Institute · USUniversity of Washington · US

Funding

Translational Research Center to Expedite Novel Therapies in Cystic FibrosisP30DK089507 · NIDDK · SEATTLE CHILDREN'S HOSPITAL · PI PRADEEP k SINGH · 2010 to 2026
$21.4M
A prospective trial of oral azithromycin when added to inhaled tobramycin in CFR01HL124053 · NHLBI · SEATTLE CHILDREN'S HOSPITAL · PI NICHOLS, DAVID PAUL · 2015 to 2019
$2.8M
Patient-oriented microbiome and advanced culture approaches to identifying the microbial determinants of chronic pediatric diseaseK24HL141669 · NHLBI · UNIVERSITY OF WASHINGTON · PI Lucas R Hoffman · 2018 to 2026
$929k
NHLBI NIH HHS K24 HL141669NHLBI NIH HHS R01 HL124053NIDDK NIH HHS P30 DK089507
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AzithromycinCystic FibrosisAdolescentAdultAnti-Bacterial AgentsChildHumansRetrospective StudiesTobramycinYoung AdultAnti-Bacterial AgentsAzithromycinTobramycinantimicrobialsazithromycinpediatricspulmonary exacerbationstobramycin

Identifiers

PMID32810412
PMCPMC7869777
OpenAlexW3054154288

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.