ArticleESC heart failure2020
Cognitive test results are associated with mortality and rehospitalization in heart failure: Swedish prospective cohort study.
Article in ESC heart failure, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed.
- L-Arginine Improves Cognitive Impairment in Hypertensive Frail Older Adults.Frontiers in cardiovascular medicine · 2022Trial
- Computerized Cognitive Training and 24-Month Mortality in Heart Failure.The Journal of cardiovascular nursingTrial
- Exploring the Relationship Between Sleep Disturbances, Gut Microbiota, and Cognition in Patients with Heart Failure: A Cross-Sectional Study.Medicina (Kaunas, Lithuania) · 2026Article
- Prevalence of cognitive impairment in older medical inpatients: A systematic review and meta-analysis.Journal of anesthesia and translational medicine · 2026Review
- Post-LVAD cognitive trajectories and determinants of non-improvement in end-stage heart failure.Journal of thoracic disease · 2026Article
- Reduced right/left ventricular blood pool T2 ratio on cardiac magnetic resonance indicates cognitive impairment in heart failure secondary to ischemic heart disease.BMC medical imaging · 2026Article
- Assessment of cognitive function in patients with heart failure: impact of clinical and sociodemographic factors.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- Association of Dementia With the Outcome of Patients With Heart Failure: Evidence From the Japanese KCHF Registry.Journal of the American Heart Association · 2025Observational
- Program theory and economic insights of a comprehensive geriatric assessment for frail heart failure patients.BMC geriatrics · 2025Article
- Feasibility of telephone and computerized cognitive testing as a secondary outcome in an acute stroke clinical trial: A mixed methods sub-study of the AcT Trial.European stroke journal · 2025Article
- Determinants of Cognitive Performance Among Ghanaian Hypertensive Patients: A Cross-Sectional Study.Health science reports · 2025Article
- Incremental Prognostic Value of Hippocampal Metabolic Activity for Sudden Cardiac Death in Patients With Heart Failure With Reduced Ejection Fraction.Journal of the American Heart Association · 2025Article
- The Heart-Brain Axis: Key Concepts in Neurocardiology.Cardiology discovery · 2025Review
- Effects of long-term mindfulness meditation training on attentional capacity in professional male fencer athletes.Scientific reports · 2025Article
- Article
- Trajectory of Cardiogenic Dementia: A New Perspective.Journal of cellular and molecular medicine · 2025Review
- Impact of cognitive impairment on heart failure prognosis: insights into central nervous system mechanism.EJNMMI research · 2024Article
- Factors Influencing the Development and Severity of Cognitive Decline in Patients with Chronic Heart Failure.Medicina (Kaunas, Lithuania) · 2024Article
- Mapping research on cognitive impairment in heart failure patients: A bibliometric analysis from 2013 to 2022.Heliyon · 2024Review
- Long-term cognitive and brain morphologic changes in chronic heart failure: Results of the Cognition.Matters-HF study.ESC heart failure · 2024Article
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Authors and funding
10 authors.
Funding
Abstract
aimsWe aimed to search for associations between cognitive test results with mortality and rehospitalization in a Swedish prospective heart failure (HF) patient cohort. METHODS AND
resultsTwo hundred and eighty-one patients hospitalized for HF (mean age, 74 years; 32% women) were assessed using cognitive tests: Montreal Cognitive Assessment (MoCA), A Quick Test of Cognitive speed, Trail Making Test A, and Symbol Digit Modalities Test. The mean follow-up time censored at rehospitalization or death was 13 months (interquartile range, 14) and 28 months (interquartile range, 29), respectively. Relations between cognitive test results, mortality, and rehospitalization risk were analysed using multivariable Cox regression model adjusted for age, sex, body mass index, systolic blood pressure, atrial fibrillation, diabetes, smoking, educational level, New York Heart Association class, and prior cardiovascular disease. A total of 80 patients (29%) had signs of cognitive impairment (MoCA score < 23 points). In the fully adjusted Cox regression model using standardized values per 1 SD change of each cognitive test, lower score on MoCA [hazard ratio (HR), 0.75; confidence interval (CI), 0.60-0.95; P = 0.016] and Symbol Digit Modalities Test (HR, 0.66; CI, 0.48-0.90; P = 0.008) yielded significant associations with increased mortality. Rehospitalization risk (n = 173; 62%) was significantly associated with lower MoCA score (HR, 0.84; CI, 0.71-0.99; P = 0.033).
conclusionsTwo included cognitive tests were associated with mortality in hospitalized HF patients, independently of traditional risk factors. In addition, worse cognitive test scores on MoCA heralded increased risk of rehospitalization.
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