ReviewAdvances in therapy2020
Novel Insights into the Transmission of SARS-CoV-2 Through the Ocular Surface and its Detection in Tears and Conjunctival Secretions: A Review.
Review in Advances in therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 30 citations in OpenAlex.
- Detection of coronavirus in tear samples of hospitalized patients with COVID-19.International ophthalmology · 2023Article
- The Outbreak of Acute Primary Angle-Closure Cases During the COVID-19 Omicron Variant Pandemic at a Tertiary Eye Center in Shanghai.Clinical ophthalmology (Auckland, N.Z.) · 2023Article
- In vitro inactivation of SARS-CoV-2 using a povidone-iodine oral rinse.BMC oral health · 2022Article
- Conjunctivitis as a sign of persistent SARS-COV-2 infection? An observational study and report of late symptoms.European journal of ophthalmology · 2021Article
- SARS-CoV-2 in Conjunctiva and Tears and Ocular Symptoms of Patients with COVID-19.Vision (Basel, Switzerland) · 2021Article
- Inhibitory Effect of Ophthalmic Solutions against SARS-CoV-2: A Preventive Action to Block the Viral Transmission?Microorganisms · 2021Article
- Pathophysiology of infection with SARS-CoV-2-What is known and what remains a mystery.Respirology (Carlton, Vic.) · 2021Review
- Quantitative Evaluation of Aerosol Generation from Non-contact Tonometry and its Correlation with Tear Film Characteristics.Advances in therapy · 2021Article
- Ocular Involvement of SARS-CoV-2 in a Polish Cohort of COVID-19-Positive Patients.International journal of environmental research and public health · 2021Article
- Mechanisms of COVID-19-induced heart failure: a short review.Heart failure reviews · 2021Review
- Systemic diseases and the cornea.Experimental eye research · 2021Review
- Testing the Sensitivity of Conjunctival Swabs from Confirmed COVID-19 Patients.Clinical ophthalmology (Auckland, N.Z.) · 2021Article
- Evidence of SARS-CoV-2 Transmission Through the Ocular Route.Clinical ophthalmology (Auckland, N.Z.) · 2021Review
- SARS-CoV-2 RNA and antibodies in tear fluid.BMJ open ophthalmology · 2021Article
- Microdroplet and spatter contamination during phacoemulsification cataract surgery in the era of COVID-19.Clinical & experimental ophthalmology · 2020Article
- Hypercytokinemia in COVID-19: Tear cytokine profile in hospitalized COVID-19 patients.Experimental eye research · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
SARS-CoV-2 is a highly transmissible virus that spreads mainly via person-to-person contact through respiratory droplets, or through contact with contaminated objects or surfaces from an infected person. At present we are passing through a phase of slow and painful understanding of the origin, epidemiological profile, clinical spectrum, and risk profile of the virus. To the best of our knowledge there is only limited and contradictory evidence concerning SARS-CoV-2 transmission through other routes. Importantly, the eye may constitute not only a potential site of virus replication but also an alternative transmission route of the virus from the ocular surface to the respiratory and gastrointestinal tract. It is therefore imperative to gain a better insight into the potential ophthalmological transmission route of the virus and establish directions on best practice and future models of care for ophthalmological patients. This review article critically evaluates available evidence on the ophthalmological mode of viral transmission and the value of earlier identification of the virus on the eye. More evidence is urgently needed to better evaluate the need for protective measures and reliable ocular diagnostic tests to diminish further pandemic spread.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.