Evidence map›Paper›PMID 32809207›Full record

ArticleJournal of ultrasound2021

Early detection of deep vein thrombosis in patients with coronavirus disease 2019: who to screen and who not to with Doppler ultrasound?

Anna Maria Ierardi, Andrea Coppola, Stefano Fusco, Elvira Stellato, Stefano Aliberti, Maria Carmela Andrisani, Valentina Vespro, Antonio Arrichiello, Mauro Panigada, Valter Monzani and 7 more

Abstract read
In one paragraph

Article in Journal of ultrasound, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Asthma in patients with coronavirus disease 2019: A systematic review and meta-analysis.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2021
    Pooled it
  3. Pooled it
  4. Pulmonary Embolism Does Not Have an Unusually High Incidence Among Hospitalized COVID19 Patients.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Pooled it
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Screening for venous thromboembolism in patients with COVID-19.Journal of thrombosis and thrombolysis · 2021
    Review
  12. Article
  13. Article
  14. High prevalence of occult thrombosis in cases of mild/moderate COVID-19.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Anna Maria IerardiRadiology Department, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Via Francesco Sforza 35, 20122, Milan, Italy. amierardi@yahoo.it.ORCID http://orcid.org/0000-0002-4160-8018
Andrea CoppolaRadiology Unit, Ospedale di Circolo e Fondazione Macchi, Insubria University, Varese, Italy.
Stefano FuscoRadiology Department, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Via Francesco Sforza 35, 20122, Milan, Italy.
Elvira StellatoRadiology Department, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Via Francesco Sforza 35, 20122, Milan, Italy.
Stefano AlibertiUOC Pneumologia, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Maria Carmela AndrisaniRadiology Department, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Via Francesco Sforza 35, 20122, Milan, Italy.
Valentina VesproRadiology Department, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Via Francesco Sforza 35, 20122, Milan, Italy.
Antonio ArrichielloRadiology Department, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Via Francesco Sforza 35, 20122, Milan, Italy.
Mauro PanigadaDepartment of Anesthesia and Critical Care, Fondazione IRCCS Ca' Granda, Ospedale Maggiore, Milan, Italy.
Valter MonzaniDepartment of Internal Medicine, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.
Giacomo GrasselliDepartment of Anesthesia and Critical Care, Fondazione IRCCS Ca' Granda, Ospedale Maggiore, Milan, Italy.
Massimo VenturiniRadiology Unit, Ospedale di Circolo e Fondazione Macchi, Insubria University, Varese, Italy.
Bhavya RehaniDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA.
Flora PeyvandiFondazione IRCCS Ca' Granda Ospedale Maggiore, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Fondazione Luigi Villa, Milan, Italy.
Antonio PesentiDepartment of Anesthesia and Critical Care, Fondazione IRCCS Ca' Granda, Ospedale Maggiore, Milan, Italy.
Francesco BlasiUOC Pneumologia, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Gianpaolo CarrafielloRadiology Department, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Via Francesco Sforza 35, 20122, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAim of the study is to evaluate the incidence of DVT in COVID-19 patients and its correlation with the severity of the disease and with clinical and laboratory findings.

methods234 symptomatic patients with COVID-19, diagnosed according to the World Health Organization guidelines, were included in the study. The severity of the disease was classified as moderate, severe and critical. Doppler ultrasound (DUS) was performed in all patients. DUS findings, clinical, laboratory's and therapeutic variables were investigated by contingency tables, Pearson chi square test and by Student t test and Fisher's exact test. ROC curve analysis was applied to study significant continuous variables.

resultsOverall incidence of DVT was 10.7% (25/234): 1.6% (1/60) among moderate cases, 13.8% (24/174) in severely and critically ill patients. Prolonged bedrest and intensive care unit admission were significantly associated with the presence of DVT (19.7%). Fraction of inspired oxygen, P/F ratio, respiratory rate, heparin administration, D-dimer, IL-6, ferritin and CRP showed correlation with DVT.

conclusionDUS may be considered a useful and valid tool for early identification of DVT. In less severely affected patients, DUS as screening of DVT might be unnecessary. High rate of DVT found in severe patients and its correlation with respiratory parameters and some significant laboratory findings suggests that these can be used as a screening tool for patients who should be getting DUS.

Indexed as

AdultAgedCOVID-19C-Reactive ProteinCritical IllnessEarly DiagnosisFerritinsFibrin Fibrinogen Degradation ProductsHeparinHumansIncidenceIntensive Care UnitsInterleukin-6MaleMiddle AgedOxygenC-Reactive ProteinFerritinsFibrin Fibrinogen Degradation Productsfibrin fragment DHeparinInterleukin-6OxygenCOVID-19Doppler; diagnosisPandemicsUltrasonographyVenous thrombosis

Identifiers

PMID32809207
PMCPMC7431752

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.