ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2021
Matrix-assisted chondrocyte transplantation with bone grafting for knee osteochondritis dissecans: stable results at 12 years.
Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05332288 (Triphasic Osteochondral Scaffold for the Treatment of Osteochondritis Dissecans of the Knee), which is not on this map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Triphasic Osteochondral Scaffold for the Treatment of Osteochondritis Dissecans of the Knee: Observational Study
Who cites it
10 citing papers in PubMed, 26 citations in OpenAlex.
- Management and Outcomes of Osteochondritis Dissecans of the Knee in the Pediatric and Adolescent Population.Current reviews in musculoskeletal medicine · 2026Review
- Good reintegration of unstable osteochondritis dissecans at the femoral condyle following screw fixation: A 3-year magnetic resonance imaging and clinical follow-up study.Journal of experimental orthopaedics · 2025Article
- Autologous bone grafting combined with spheroid-based matrix-induced autologous chondrocyte implantation for osteochondral defects of the knee: Good clinical outcomes alongside abnormal postoperative gait patterns.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025Article
- Revision Surgery Is the Most Common Definition of Failure in Studies Evaluating Knee Cartilage Restoration Outcomes: A Systematic Review.Arthroscopy, sports medicine, and rehabilitation · 2025Review
- Arthroscopic Assisted Surgical Technique of Impaction Bone Grafting and Autologous Matrix-Induced Chondrogenesis for Deep Osteochondral Knee Defects.Arthroscopy techniques · 2025Article
- Single-plug osteochondral autograft transplantation for knee osteochondritis dissecans: Clinical improvement and long-term survivorship at a minimum ten year follow-up.International orthopaedics · 2024Article
- Matrix-Assisted Autologous Chondrocyte Transplantation for the Treatment of Patellofemoral Chondral Lesions: Long-term Results at a Minimum 15-Year Follow-up.The American journal of sports medicine · 2024Article
- Clinical Outcomes and Return-to-Sport Rates following Fragment Fixation Using Hydroxyapatite/Poly-L-Lactate Acid Threaded Pins for Knee Osteochondritis Dissecans: A Case Series.Biomimetics (Basel, Switzerland) · 2024Article
- Satisfactory patient-reported outcomes in patients treated with impaction bone grafting and autologous matrix-induced chondrogenesis for osteochondral knee defects.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023Article
- Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo document clinical and radiological results of arthroscopic matrix-assisted autologous chondrocyte transplantation (MACT) combined with bone grafting for the treatment of knee osteochondritis dissecans (OCD) at long-term follow-up.
methodsThirty-one knees in 29 patients (20.4 ± 5.7 years) were treated for symptomatic unfixable OCD lesions (2.6 ± 1.1 cm
resultsBeside 4 early failures, an overall clinical improvement was documented: the IKDC subjective score improved from 39.9 ± 16.8 to 82.1 ± 17.0 and 84.8 ± 17.2 at 2 and 5 years, respectively (p < 0.0005), and remained stable for up to 12 years (85.0 ± 20.2). EQ-VAS and Tegner scores presented similar trends, but patients did not reach their original activity level. Worse results were obtained for lesions bigger than 4 cm
conclusionsArthroscopic bone grafting followed by MACT for unfixable knee OCD can offer a promising and stable clinical outcome over time in lesions smaller than 4 cm LEVEL OF EVIDENCE: IV.
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Registered trials
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